Moon S Y, Woolson R F, Bean J A
Comput Programs Biomed. 1979 Sep;10(2):91-104. doi: 10.1016/0010-468x(79)90056-4.
PROPHAZ is a computer program created for the analysis of survival data using the general proportional hazards model. It was designed specifically for the situation in which the underlying hazard function may be estimated from the mortality experience of a large reference population, but may be used for other problems as well. Input for the program includes the variables of interest as well as the information necessary for estimating the hazard function (demographic and mortality data). Regression coefficients for the variables of interest are obtained iteratively using the Newton-Raphson method. Utilizing large sample asymptotic theory, x2 statistics are derived which may be used to test hypotheses of the form C beta = 0. Input format is completely flexible for the variables of interest as well as the mortality data.
PROPHAZ是一个用于使用一般比例风险模型分析生存数据的计算机程序。它是专门为以下情况设计的：潜在风险函数可根据大量参考人群的死亡经验进行估计，但也可用于其他问题。该程序的输入包括感兴趣的变量以及估计风险函数所需的信息（人口统计学和死亡率数据）。使用牛顿-拉弗森方法迭代获得感兴趣变量的回归系数。利用大样本渐近理论，推导出可用于检验形式为Cβ = 0的假设的卡方统计量。对于感兴趣的变量和死亡率数据，输入格式完全灵活。
