Smith E O, Hardy R J, Cooper C J, Hawkins C M
Comput Programs Biomed. 1980 Dec;12(2-3):129-40. doi: 10.1016/0010-468x(80)90059-8.
This paper presents a computer program for estimating transition rates between states in a two-compartment Markov process, where the rates are functions of covariates. Parameters are estimated by the method of maximum likelihood using the Newton-Raphson iterative procedure. The program provides statistics for testing hypotheses concerning regression coefficients and calculates observed versus expected values in order to assess the fit of the model to the data.
本文提出了一个计算机程序，用于估计两室马尔可夫过程中状态之间的转移率，其中转移率是协变量的函数。参数通过使用牛顿 - 拉弗森迭代过程的最大似然法进行估计。该程序提供用于检验关于回归系数的假设的统计量，并计算观测值与期望值，以便评估模型对数据的拟合程度。
