来自绵羊布鲁氏菌、犬流产病菌及其他布鲁氏菌属物种的脱氧核糖核酸的同源性。
Homologies of deoxyribonucleic acids from Brucella ovis, canine abortion organisms, and other Brucella species.
作者信息
Hoyer B H, McCullough N B
出版信息
J Bacteriol. 1968 Nov;96(5):1783-90. doi: 10.1128/jb.96.5.1783-1790.1968.
Abstract
The bacterium that causes canine abortion has polynucleotide sequences similar, in deoxyribonucleic acid (DNA)-DNA homology studies, to those of Brucella suis and, by inference from previous data, those of B. abortus and B. melitensis as well as B. neotomae. Therefore, the organism causing canine abortion appears to be a member of the genus Brucella. DNA preparations from Serratia marcescens, Alcaligenes faecalis, and Bordetella bronchiseptica, 58, 62, and 66 mole% guanine plus cytosine, respectively, do not have detectable polynucleotide sequence homologies with B. suis DNA which is 56 mole% guanine plus cytosine. B. ovis DNA lacks some of the polynucleotide sequences present in B. suis DNA and appears to be a deletion mutant. However, a large proportion of B. ovis polynucleotides are similar to those of other Brucella species, which supports the inclusion of B. ovis in the genus.
摘要
在脱氧核糖核酸（DNA）-DNA同源性研究中，导致犬流产的细菌具有与猪布鲁氏菌相似的多核苷酸序列，并且根据先前的数据推断，它与流产布鲁氏菌、羊布鲁氏菌以及新墨西哥布鲁氏菌的多核苷酸序列也相似。因此，导致犬流产的病原体似乎是布鲁氏菌属的一个成员。粘质沙雷氏菌、粪产碱菌和支气管败血波氏杆菌的DNA制剂，鸟嘌呤加胞嘧啶的含量分别为58%、62%和66%，与鸟嘌呤加胞嘧啶含量为56%的猪布鲁氏菌DNA没有可检测到的多核苷酸序列同源性。绵羊布鲁氏菌DNA缺乏猪布鲁氏菌DNA中存在的一些多核苷酸序列，似乎是一个缺失突变体。然而，绵羊布鲁氏菌的大部分多核苷酸与其他布鲁氏菌物种的多核苷酸相似，这支持将绵羊布鲁氏菌归入该属。
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