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改善原发性高血压患者药物依从性策略的随机临床试验

Randomised clinical trial of strategies for improving medication compliance in primary hypertension.

作者信息

Sackett D L, Haynes R B, Gibson E S, Hackett B C, Taylor D W, Roberts R S, Johnson A L

出版信息

Lancet. 1975 May 31;1(7918):1205-7. doi: 10.1016/s0140-6736(75)92192-3.

Abstract

230 Canadian steelworkers with hypertension took part in a randomised trial to see if compliance with antihypertensive drug regimens could be improved. For care and follow-up these men were randomly allocated to see either their own family doctors outside working-hours or industrial physicians during work shifts; the same men were randomly allocated to receive or not receive an educational programme aimed at instructing them about hypertension and its treatment. Surprisingly, the convenience of follow-up at work had no effect upon these men's compliance with antihypertensive drug regimens. Similarly, although men receiving health education learned a lot about hypertension, they were not more likely to take their medicine.

摘要

230名患有高血压的加拿大钢铁工人参与了一项随机试验,以探究是否可以提高对抗高血压药物治疗方案的依从性。为了进行护理和随访,这些男性被随机分配,要么在工作时间之外去看自己的家庭医生,要么在轮班期间去看工业医生;同样,这些男性被随机分配接受或不接受一项旨在指导他们了解高血压及其治疗方法的教育计划。令人惊讶的是,在工作场所进行随访的便利性对这些男性遵守抗高血压药物治疗方案没有影响。同样,尽管接受健康教育的男性对高血压有了很多了解,但他们服药的可能性并没有增加。

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