含醋酸盐的腹膜透析液对细菌的不良影响。
Adverse effect on bacteria of peritoneal dialysis solutions that contain acetate.
作者信息
Richardson J A, Borchardt K A
出版信息
Br Med J. 1969 Sep 27;3(5673):749-50. doi: 10.1136/bmj.3.5673.749.
Abstract
Peritoneal dialysis solutions which contained 43 mEq per litre of acetate had a greater antibacterial effect than those containing lactate. Bacteria were isolated from 15 separate clinical infections, each caused by Escherichia coli, Pseudomonas sp., or Staphylo-coccus aureus. Incubation in the dialysate made with acetate substantially reduced the number of viable organisms from all but one of the 45 isolates. It is suggested that solutions made with acetate may provide greater protection from peritonitis.
摘要
每升含有43毫当量乙酸盐的腹膜透析液比含有乳酸盐的腹膜透析液具有更强的抗菌效果。从15例分别由大肠杆菌、假单胞菌属或金黄色葡萄球菌引起的临床感染中分离出细菌。用乙酸盐配制的透析液孵育后，45株分离菌中除1株外，其余所有菌株的活菌数量均大幅减少。有人认为，用乙酸盐配制的溶液可能对腹膜炎有更好的防护作用。
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