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南欧的多发性硬化症。II:1978年马耳他的患病率。

Multiple sclerosis in southern Europe. II: Prevalence in Malta in 1978.

作者信息

Vassallo L, Elian M, Dean G

出版信息

J Epidemiol Community Health. 1979 Jun;33(2):111-3. doi: 10.1136/jech.33.2.111.

Abstract

After an intensive survey only 14 patients have been found with a diagnosis of probable multiple sclerosis (MS) in the islands of Malta. This is a low prevalence of 4.2 per 100 000. The low prevalence of MS is confirmed by the small number of deaths certified as due to MS--six in 11 years--and by the absence of Maltese MS patients resident in England among the MS patients admitted to hospital in Greater London and the West Midlands (1960-72). The low prevalence of MS found in Malta can be contrasted with the high prevalence found in Enna city in central Sicily. The genetic and environmental reasons for this difference in MS prevalence between the neighbouring islands of Sicily and Malta require further study.

摘要

经过深入调查,在马耳他群岛仅发现14例确诊为可能患有多发性硬化症(MS)的患者。患病率较低,为每10万人中4.2例。MS的低患病率可通过经证明死于MS的人数较少(11年中有6例)以及在大伦敦和西米德兰兹郡住院的MS患者中没有居住在英格兰的马耳他MS患者得到证实(1960 - 1972年)。在马耳他发现的MS低患病率与西西里岛中部恩纳市发现的高患病率形成对比。西西里岛和马耳他这两个相邻岛屿之间MS患病率存在差异的遗传和环境原因需要进一步研究。

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