用溴隐亭和左旋多巴治疗的帕金森病患者的脑电图睡眠模式：一项比较研究。
EEG sleep patterns in Parkinsonian patients treated with bromocryptine and L-dopa: a comparative study.
作者信息
Vardi J, Glaubman H, Rabey J, Streifler M
出版信息
J Neural Transm. 1979;45(4):307-16. doi: 10.1007/BF01247147.
PMID:490153
Abstract
The nocturnal sleep patterns of six Parkinsonian patients treated with Bromocryptine (2-Br-L-ergocryptine CB-154), a dopamine-like agonist, were compared with those of the same patients under L-DOPA treatment. No significant differences were found between the two groups. It is suggested that Bromocryptine, acting on dopamine receptors in the sleep regulating systems at the reticular level in the midbrain has the same effect on sleep patterns of Parkinsonian patients as L-DOPA.
摘要
将六名接受多巴胺样激动剂溴隐亭（2-溴-L-麦角隐亭CB-154）治疗的帕金森病患者的夜间睡眠模式，与这些患者接受左旋多巴治疗时的睡眠模式进行了比较。两组之间未发现显著差异。提示溴隐亭作用于中脑网状水平睡眠调节系统中的多巴胺受体，对帕金森病患者睡眠模式的影响与左旋多巴相同。
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