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用溴隐亭和左旋多巴治疗的帕金森病患者的脑电图睡眠模式:一项比较研究。

EEG sleep patterns in Parkinsonian patients treated with bromocryptine and L-dopa: a comparative study.

作者信息

Vardi J, Glaubman H, Rabey J, Streifler M

出版信息

J Neural Transm. 1979;45(4):307-16. doi: 10.1007/BF01247147.

DOI:10.1007/BF01247147
PMID:490153
Abstract

The nocturnal sleep patterns of six Parkinsonian patients treated with Bromocryptine (2-Br-L-ergocryptine CB-154), a dopamine-like agonist, were compared with those of the same patients under L-DOPA treatment. No significant differences were found between the two groups. It is suggested that Bromocryptine, acting on dopamine receptors in the sleep regulating systems at the reticular level in the midbrain has the same effect on sleep patterns of Parkinsonian patients as L-DOPA.

摘要

将六名接受多巴胺样激动剂溴隐亭(2-溴-L-麦角隐亭CB-154)治疗的帕金森病患者的夜间睡眠模式,与这些患者接受左旋多巴治疗时的睡眠模式进行了比较。两组之间未发现显著差异。提示溴隐亭作用于中脑网状水平睡眠调节系统中的多巴胺受体,对帕金森病患者睡眠模式的影响与左旋多巴相同。

相似文献

1
EEG sleep patterns in Parkinsonian patients treated with bromocryptine and L-dopa: a comparative study.用溴隐亭和左旋多巴治疗的帕金森病患者的脑电图睡眠模式:一项比较研究。
J Neural Transm. 1979;45(4):307-16. doi: 10.1007/BF01247147.
2
EEG sleep study in parkinsonian patients under bromocryptine treatment.帕金森病患者接受溴隐亭治疗时的脑电图睡眠研究。
Eur Neurol. 1978;17(6):345-50. doi: 10.1159/000114973.
3
Myoclonic attacks induced by L-dopa and bromocryptin in Parkinson patients: a sleep EEG study.左旋多巴和溴隐亭诱发帕金森病患者肌阵挛发作:一项睡眠脑电图研究。
J Neurol. 1978 Apr 14;218(1):35-42. doi: 10.1007/BF00314716.
4
Lisuride and bromocryptine in L-Dopa stable-responder parkinsonian patients: a comparative, double-blind evaluation of cardiopressor and neurochemical effects.左旋多巴稳定反应型帕金森病患者使用利苏瑞ide和溴隐亭:对心脏升压作用和神经化学效应的比较性双盲评估
Funct Neurol. 1996 Nov-Dec;11(6):317-25.
5
Brain dopamine receptor stimulation and the relief of Parkinsonism: relationship between bromocriptine and levodopa.脑多巴胺受体刺激与帕金森病症状缓解:溴隐亭与左旋多巴之间的关系。
Ann Neurol. 1978 Sep;4(3):263-7. doi: 10.1002/ana.410040313.
6
[Letter: Effect of bromocryptine on the fluctuations following dopa therapy. On-off phenomenon in parkinsonian patients].[信件:溴隐亭对左旋多巴治疗后波动的影响。帕金森病患者的开关现象]
Nouv Presse Med. 1976;5(28):1761.
7
Bromocriptine lessens the incidence of mortality in L-dopa-treated parkinsonian patients: prado-study discontinued.溴隐亭可降低左旋多巴治疗的帕金森病患者的死亡率:普拉多研究已停止。
Eur J Clin Pharmacol. 1992;43(4):357-63. doi: 10.1007/BF02220609.
8
Bromocriptine and dopamine receptor stimulation.溴隐亭和多巴胺受体刺激。
Br J Clin Pharmacol. 1976 Dec;3(6):977-82. doi: 10.1111/j.1365-2125.1976.tb00346.x.
9
Combined L-dopa and bromocriptine therapy for Parkinson's disease: a proposed mechanism of action.左旋多巴与溴隐亭联合治疗帕金森病:一种作用机制的探讨
Clin Neuropharmacol. 1987 Aug;10(4):384-7. doi: 10.1097/00002826-198708000-00010.
10
Dopamine receptors: effects of chronic L-dopa and bromocriptine treatment in an animal model of Parkinson's disease.多巴胺受体:左旋多巴和溴隐亭长期治疗对帕金森病动物模型的影响
Clin Neuropharmacol. 1984;7(3):247-57.

引用本文的文献

1
Sleep disturbances in Parkinson's disease patients and management options.帕金森病患者的睡眠障碍及治疗选择。
Nat Sci Sleep. 2011 Dec 1;3:125-33. doi: 10.2147/NSS.S18897. Print 2011.
2
Changes in nocturnal sleep in Huntington's and Parkinson's disease.亨廷顿氏病和帕金森氏病患者夜间睡眠的变化。
J Neurol. 1988 Jan;235(3):177-9. doi: 10.1007/BF00314313.

本文引用的文献

1
L-dopa: effect on concentrations of dopamine, norepinephrine, and serotonin in brains of mice.L-多巴:对小鼠脑内多巴胺、去甲肾上腺素和 5-羟色胺浓度的影响。
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[Distribution of 5-hydroxytryptamine (serotonin) in the human brain and its behavior in patients with Parkinson's syndrome].[5-羟色胺(血清素)在人脑中的分布及其在帕金森综合征患者中的表现]
Klin Wochenschr. 1961 Oct 15;39:1056-9. doi: 10.1007/BF01487648.
3
Proposed supplements and amendments to 'A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects', the Rechtschaffen & Kales (1968) standard.
对《人类受试者睡眠阶段标准化术语、技术和评分系统手册》( Rechtschaffen和Kales,1968年标准)的拟议补充和修订。
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4
The effect of L-dopa on the concentrations of tryptophan, tyrosine and serotonin in rat brain.左旋多巴对大鼠脑内色氨酸、酪氨酸和血清素浓度的影响。
Eur J Pharmacol. 1971 May;14(4):393-6. doi: 10.1016/0014-2999(71)90195-6.
5
Monoamines in the human neostriatum: topographic distribution in normals and in Parkinson's disease and their role in akinesia, rigidity, chorea, and tremor.人类新纹状体中的单胺:正常人和帕金森病患者的地形分布及其在运动不能、强直、舞蹈症和震颤中的作用。
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L-DOPA treatment in Parkinson's disease: effect on dopamine and related substances in discrete brain regions.左旋多巴治疗帕金森病:对不同脑区多巴胺及相关物质的影响。
Experientia. 1971 Sep 15;27(9):1048-9. doi: 10.1007/BF02138873.
7
Treatment of Parkinson's disease with levodopa and Ro 4-4602.左旋多巴和Ro 4-4602治疗帕金森病
Clin Pharmacol Ther. 1971 Mar-Apr;12(2):353-9. doi: 10.1002/cpt1971122part2353.
8
Similarities between neurologic effects of L-dopa and of apomorphine.左旋多巴与阿扑吗啡对神经系统作用的相似性。
N Engl J Med. 1970 Jan 1;282(1):31-3. doi: 10.1056/NEJM197001012820107.
9
Treatment of Parkinson's disease with levodopa combined with L-alpha-methyldopahydrazine, an inhibitor of extracerebral DOPA decarboxylase.左旋多巴联合脑外多巴脱羧酶抑制剂L-α-甲基多巴肼治疗帕金森病。
J Neurol Neurosurg Psychiatry. 1973 Feb;36(1):10-4. doi: 10.1136/jnnp.36.1.10.
10
L-dopa in Parkinsonism. A possible mechanism of action.帕金森病中的左旋多巴。一种可能的作用机制。
Neurology. 1972 Jul;22(7):688-96. doi: 10.1212/wnl.22.7.688.