Klein G C, Baker C N, Moody M D
Appl Microbiol. 1970 Jan;19(1):60-1. doi: 10.1128/am.19.1.60-61.1970.
This report describes a comparison of the Behringwerke antistreptolysin O (ASO) latex screening test with the ASO hemolytic test. Agreement between the two tests was poor when Difco streptolysin O (SLO) reagent was employed in the hemolytic test; approximately 34% of the sera with ASO titers in the normal range of the hemolytic test gave false-positive latex test reactions. However, the percentage of false-positive latex test reactions was only 5% when Behringwerke SLO reagent was used in the hemolytic test. An assay of the Difco and Behringwerke SLO reagents against an ASO standard indicated that the Difco SLO reagent was more potent than the Behringwerke SLO reagent. The lack of agreement between the Behringwerke latex test and the hemolytic test using Difco SLO reagent is attributed to the potency of the SLO reagents.
本报告描述了贝林werke抗链球菌溶血素O（ASO）乳胶筛查试验与ASO溶血试验的比较。当在溶血试验中使用Difco链球菌溶血素O（SLO）试剂时，两种试验之间的一致性较差；在溶血试验正常范围内ASO滴度的血清中，约34%产生了乳胶试验假阳性反应。然而，当在溶血试验中使用贝林werke SLO试剂时，乳胶试验假阳性反应的百分比仅为5%。针对ASO标准品对Difco和贝林werke SLO试剂进行的测定表明，Difco SLO试剂比贝林werke SLO试剂效力更强。贝林werke乳胶试验与使用Difco SLO试剂的溶血试验之间缺乏一致性归因于SLO试剂的效力。
