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胰腺分泌与胰腺血流之间的关系。

Relationship between pancreatic secretion and pancreatic blood flow.

作者信息

Goodhead B, Himal H S, Zanbilowicz J

出版信息

Gut. 1970 Jan;11(1):62-8. doi: 10.1136/gut.11.1.62.

Abstract

An indicator fractionation technique using radioactive rubidium has been used to measure pancreatic blood flow after infusions of secretin, pancreozymin, urecholine, and pentagastrin. Secretin resulted in the production of a large volume of low viscous pancreatic juice and was associated with an increase in the cardiac output. Duodenal and pancreatic blood flow and perfusion rate were increased significantly. Blood flow to the remainder of the gastrointestinal organs was only marginally increased but the perfusion rate in each organ was increased significantly.Infusion of pancreozymin, urecholine, and pentagastrin resulted in the output of a small volume of viscous juice and was associated with no increase in cardiac output but with an increase in both pancreatic blood flow and perfusion rate.

摘要

一种使用放射性铷的示踪剂分离技术已被用于测量在输注促胰液素、胰酶泌素、乌拉胆碱和五肽胃泌素后胰腺的血流情况。促胰液素导致大量低粘度胰液的分泌,并伴有心输出量增加。十二指肠和胰腺的血流及灌注率显著增加。胃肠道其他器官的血流仅略有增加,但每个器官的灌注率显著增加。输注胰酶泌素、乌拉胆碱和五肽胃泌素导致少量粘稠胰液的分泌,且不伴有心输出量增加,但胰腺血流和灌注率均增加。

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2
On the preparation of secretin and pancreozymin.关于促胰液素和缩胆囊素的制备。
J Physiol. 1949 Dec;110(3-4):367-76. doi: 10.1113/jphysiol.1949.sp004445.

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