Hossmann K A, Sato K
Science. 1970 Apr 17;168(3929):375-6. doi: 10.1126/science.168.3929.375.
Cats were submitted to complete cerebral ischemia by clamping the innominate and subclavian arteries and simultaneously lowering the systemic blood pressure. Neuronal function was assessed by recording the electroencephalogram and the anti- and orthodromic activation of the pyramidal tract. A full recovery of the pyramidal response and even of evoked electroencephalographic activity occurred after ischemia of more than 1 hour's duration.
通过夹闭无名动脉和锁骨下动脉并同时降低体循环血压,使猫处于完全脑缺血状态。通过记录脑电图以及锥体束的逆向和顺向激活来评估神经元功能。在持续超过1小时的缺血后,锥体反应甚至诱发的脑电图活动完全恢复。