一种攻击T4 DNA的T4诱导的核酸内切酶。
A T4-induced endonuclease which attacks T4 DNA.
作者信息
Altman S, Meselson M
出版信息
Proc Natl Acad Sci U S A. 1970 Jul;66(3):716-21. doi: 10.1073/pnas.66.3.716.
Abstract
A DNA endonucleolytic activity that introduces single-stranded breaks into native T4 DNA is found in T4-infected E. coli. This endonuclease attacks other double-stranded, but not single-stranded, DNA. Experiments with ultraviolet-irradiated phages and amber mutants indicate that the enzyme is made beginning about five minutes after infection at 37 degrees C.
摘要
在受T4感染的大肠杆菌中发现了一种能在天然T4 DNA中引入单链断裂的DNA内切核酸酶活性。这种内切核酸酶能攻击其他双链DNA，但不能攻击单链DNA。用紫外线照射的噬菌体和琥珀突变体进行的实验表明，该酶在37摄氏度感染后约五分钟开始产生。
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本文引用的文献
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Early enzyme synthesis and its control in E. coli infected with some amber mutants of bacteriophage T4.用噬菌体T4的一些琥珀突变体感染大肠杆菌后早期酶的合成及其调控
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Glucosylation of deoxyribonucleic acid by enzymes from bacteriophage-infected Escherichia coli.噬菌体感染的大肠杆菌中酶对脱氧核糖核酸的糖基化作用。
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Molecular recombination in T4 bacteriophage deoxyribonucleic acid. I. Tertiary structure of early replicative and recombining deoxyribonucleic acid.T4噬菌体脱氧核糖核酸中的分子重组。I. 早期复制和重组脱氧核糖核酸的三级结构。
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