Hodgkin G K, Freedman R, Fuller I, Whewell J
Br Med J. 1970 Aug 15;3(5719):368-71. doi: 10.1136/bmj.3.5719.368.
A survey of recurrent indigestion in four general practices (19,619 patients) showed a wide range of dyspeptic complaints. Of these 82 (4.2 per 1,000) already had a proved ulcer and 144 (7.3 per 1,000) had symptoms suggesting a duodenal ulcer and had either not been investigated or had previously had a normal barium meal. A duodenal ulcer was found radiologically in half the men (46 out of 95) but in only 16% of the women (8 out of 49). In 11 (25%) of the 46 men shown to have an ulcer a barium meal had been previously reported as normal. Evidence is put forward that ulcer symptoms in the large residue of patients with a normal barium meal (38 men, 29 women) were produced by a primary duodenal condition (duodenitis) of which ulcer was one complication.
一项针对四个普通诊所(19619名患者)复发性消化不良的调查显示,消化不良症状多种多样。其中82人(每1000人中有4.2人)已被证实患有溃疡,144人(每1000人中有7.3人)有十二指肠溃疡症状,但未接受过检查或之前钡餐检查结果正常。通过放射检查发现,男性中有一半(95人中有46人)患有十二指肠溃疡,而女性中只有16%(49人中有8人)患病。在经检查证实患有溃疡的46名男性中,有11人(25%)之前的钡餐检查报告显示正常。有证据表明,钡餐检查结果正常的大量患者(38名男性,29名女性)的溃疡症状是由原发性十二指肠疾病(十二指肠炎)引起的,溃疡是该疾病的一种并发症。