核糖体中RNA的结构。
Structure of RNA in ribosomes.
作者信息
Hartman K A, Amaya J, Schachter E M
出版信息
Science. 1970 Oct 9;170(3954):171-3. doi: 10.1126/science.170.3954.171.
PMID:4917385
Abstract
The 50S and 30S ribosomes and 23S and 16S RNA were hydrolyzed with ribonuclease A. The rate constants and number of fragments produced were determined for each reaction. The conformation of 23S RNA changes when the RNA is extracted from the ribosome. Specific regions of the RNA in 50S and 30S ribosomes are protected from hydrolysis by the ribosomal proteins.
摘要
50S和30S核糖体以及23S和16S RNA用核糖核酸酶A进行水解。测定每个反应的速率常数和产生的片段数量。当从核糖体中提取RNA时，23S RNA的构象会发生变化。50S和30S核糖体中RNA的特定区域受到核糖体蛋白的保护而不被水解。
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