Chan E L, Mishell R I, Mitchell G F
Science. 1970 Dec 11;170(3963):1215-7. doi: 10.1126/science.170.3963.1215.
Cytotoxic antiserum to theta antigen reduces the capacity of mouse spleen cells to generate direct and indirect plaque-forming cells to sheep erythrocytes in vitro but does not affect plaque-forming cells, their precursors, or hemopoietic stem cells. The response of spleen cells treated with antiserum to theta antigen is restored by thymus cells incubated in vivo with sheep erythrocytes.
针对θ抗原的细胞毒性抗血清可降低小鼠脾细胞在体外产生针对绵羊红细胞的直接和间接噬斑形成细胞的能力,但不影响噬斑形成细胞、其前体细胞或造血干细胞。用针对θ抗原的抗血清处理过的脾细胞的反应可通过在体内与绵羊红细胞一起孵育的胸腺细胞得以恢复。