接种冻干念珠菌细胞的小鼠全身性淀粉样变性
Systemic amyloidosis in mice inoculated with lyophilized Candida cells.
作者信息
Mann S J, Blank F
出版信息
Infect Immun. 1975 Jun;11(6):1371-4. doi: 10.1128/iai.11.6.1371-1374.1975.
Abstract
Injection of lyophilized Candida albicans or C. parapsilosis cells induced amyloidosis in outbred CFW mice. The disease process was irreversible, and a significant number of animals died of systemic amyloidosis within 400 days after the last treatment. The techniques described may represent a model system for the study of systemic amyloidosis.
摘要
注射冻干的白色念珠菌或近平滑念珠菌细胞可在远交系CFW小鼠中诱发淀粉样变性。疾病进程是不可逆的，相当数量的动物在最后一次治疗后的400天内因系统性淀粉样变性死亡。所描述的技术可能代表一种用于研究系统性淀粉样变性的模型系统。
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