小鼠淀粉样蛋白AA：与人及猴淀粉样物质的非免疫球蛋白蛋白的同源性。
Mouse amyloid protein AA: Homology with nonimmunoglobulin protein of human and monkey amyloid substance.
作者信息
Eriksen N, Ericsson L H, Pearsall N, Lagunoff D, Benditt E P
出版信息
Proc Natl Acad Sci U S A. 1976 Mar;73(3):964-7. doi: 10.1073/pnas.73.3.964.
Abstract
The major protein extracted from anyloid deposits induced in mice by injection of either Candida albicans cells or sodium caseinate was found to have chromatographic and electrophoretic properties and an amino-acid compostiion characteristic of the AA class of amyloid proteins. The homology of the mouse protein with protein AA from man and monkey was established by determination of the sequence of the first 28 amino-acid residues.
摘要
通过注射白色念珠菌细胞或酪蛋白酸钠在小鼠体内诱导产生的淀粉样沉积物中提取的主要蛋白质，被发现具有色谱和电泳特性以及AA类淀粉样蛋白的氨基酸组成特征。通过测定前28个氨基酸残基的序列，确定了小鼠蛋白与人及猴的AA蛋白的同源性。
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