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小鼠淀粉样蛋白AA：与人及猴淀粉样物质的非免疫球蛋白蛋白的同源性。

Mouse amyloid protein AA: Homology with nonimmunoglobulin protein of human and monkey amyloid substance.

作者信息

Eriksen N, Ericsson L H, Pearsall N, Lagunoff D, Benditt E P

出版信息

Proc Natl Acad Sci U S A. 1976 Mar;73(3):964-7. doi: 10.1073/pnas.73.3.964.

DOI:10.1073/pnas.73.3.964
PMID:815910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC336041/
Abstract

The major protein extracted from anyloid deposits induced in mice by injection of either Candida albicans cells or sodium caseinate was found to have chromatographic and electrophoretic properties and an amino-acid compostiion characteristic of the AA class of amyloid proteins. The homology of the mouse protein with protein AA from man and monkey was established by determination of the sequence of the first 28 amino-acid residues.

摘要

通过注射白色念珠菌细胞或酪蛋白酸钠在小鼠体内诱导产生的淀粉样沉积物中提取的主要蛋白质，被发现具有色谱和电泳特性以及AA类淀粉样蛋白的氨基酸组成特征。通过测定前28个氨基酸残基的序列，确定了小鼠蛋白与人及猴的AA蛋白的同源性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be4/336041/6f2396981b1b/pnas00672-0307-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be4/336041/5cf0314e71fd/pnas00672-0307-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be4/336041/6f2396981b1b/pnas00672-0307-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be4/336041/5cf0314e71fd/pnas00672-0307-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be4/336041/6f2396981b1b/pnas00672-0307-b.jpg

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Mouse amyloid protein AA: Homology with nonimmunoglobulin protein of human and monkey amyloid substance.小鼠淀粉样蛋白AA：与人及猴淀粉样物质的非免疫球蛋白蛋白的同源性。
Proc Natl Acad Sci U S A. 1976 Mar;73(3):964-7. doi: 10.1073/pnas.73.3.964.
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本文引用的文献

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Amino acid sequence of chymotryptic peptides from horse heart cytochrome c.马心脏细胞色素c的胰凝乳蛋白酶消化肽段的氨基酸序列。
J Biol Chem. 1962 Jul;237:2161-74.
2
The oxidation of ribonuclease with performic acid.用过甲酸氧化核糖核酸酶。
J Biol Chem. 1956 Apr;219(2):611-21.
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The major proteins of human and monkey amyloid substance: Common properties including unusual N-terminal amino acid sequences.人类和猴子淀粉样物质的主要蛋白质：共同特性，包括不寻常的N端氨基酸序列。
Amyloid. 2016;23(1):1-7. doi: 10.3109/13506129.2015.1110518. Epub 2015 Dec 8.
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Animal models of human amyloidoses: are transgenic mice worth the time and trouble?人类淀粉样变性的动物模型：转基因小鼠是否值得投入时间和精力？
FEBS Lett. 2009 Aug 20;583(16):2663-73. doi: 10.1016/j.febslet.2009.07.031. Epub 2009 Jul 20.
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Unifying features of systemic and cerebral amyloidosis.系统性和脑淀粉样变性的共同特征。
Mol Neurobiol. 1994 Feb;8(1):49-64. doi: 10.1007/BF02778007.
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Differences in the acute phase responses of serum amyloid P-component (SAP) and C3 to injections of casein or bovine serum albumin in amyloid-susceptible and -resistant mouse strains.血清淀粉样蛋白P成分（SAP）和C3在易患淀粉样变和抗淀粉样变小鼠品系中对注射酪蛋白或牛血清白蛋白的急性期反应差异。
Clin Exp Immunol. 1980 Feb;39(2):355-60.
7
Redistribution of amyloid deposits.淀粉样沉积物的重新分布。
Am J Pathol. 1980 Jun;99(3):539-50.
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Immunocytochemical identification of amyloid in formalin-fixed paraffin sections.福尔马林固定石蜡切片中淀粉样蛋白的免疫细胞化学鉴定
Histochemistry. 1981;72(2):161-71. doi: 10.1007/BF00517130.
9
Idiopathic amyloidosis in the stone marten (Martes foina): identification of amyloid fibril proteins in tissue sections using the immunoperoxidase technique.石貂（Martes foina）特发性淀粉样变性：利用免疫过氧化物酶技术鉴定组织切片中的淀粉样纤维蛋白。
Blut. 1980 Dec;41(6):465-8. doi: 10.1007/BF01007773.
10
Senile cerebral amyloid. Prealbumin as a common constituent in the neuritic plaque, in the neurofibrillary tangle, and in the microangiopathic lesion.老年脑淀粉样变。前白蛋白作为神经炎性斑块、神经原纤维缠结及微血管病变中的常见成分。
Am J Pathol. 1982 Apr;107(1):41-50.
FEBS Lett. 1971 Dec 1;19(2):169-173. doi: 10.1016/0014-5793(71)80506-9.
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5
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Proc Natl Acad Sci U S A. 1966 Feb;55(2):308-16. doi: 10.1073/pnas.55.2.308.
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Chemical classes of amyloid substance.淀粉样物质的化学类别。
Am J Pathol. 1971 Oct;65(1):231-52.
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The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils.某些淀粉样纤维主要非免疫球蛋白成分的氨基酸序列。
J Clin Invest. 1972 Oct;51(10):2773-6. doi: 10.1172/JCI107098.
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Chemical similarity among amyloid substances associated with long standing inflammation.
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