高钠血症。同种肾移植的并发症。
Hypernatremia. Complication of renal homotransplantation.
作者信息
Popovtzer M M, Pinggera W F, Holmes J H, Halgrimson C G, Starzl T E
出版信息
Arch Intern Med. 1971 Jun;127(6):1129-32. doi: 10.1001/archinte.127.6.1129.
Hypernatremia was observed in five reo cipients of renal homografts during the first postoperative week. The peak serum levels of sodium varied between 152 and 158 mEq Iliter. The postoperative diuresis was associated with sodium concentration in the urine, consistently lower than that in the extracellular water; moderate urinary hypertonicity, with urea being the main urinary solute; and urea excretion exceeding 60% of its filtered load in most instances. The inability of elaborate urine with sodium concentration equal or higher than that in the serum, possibly related to osmotic diuresis and/or altered renal hemodynamics, appears to be the primary cause responsible for the development of hypernatremia in these patients.
在术后第一周，5例同种肾移植受者出现高钠血症。血清钠峰值水平在152至158毫当量/升之间。术后利尿与尿钠浓度有关，尿钠浓度始终低于细胞外液中的钠浓度；尿呈中度高渗，尿素是主要的尿液溶质；在大多数情况下，尿素排泄超过其滤过负荷的60%。无法浓缩出钠浓度等于或高于血清钠浓度的尿液，可能与渗透性利尿和/或肾血流动力学改变有关，这似乎是这些患者发生高钠血症的主要原因。
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