用二巯丙磺钠治疗后大鼠尿液中微量元素的排泄情况。
The excretion of trace elements in rat urine after treatment with 2,3-dimercaptopropane sodium sulfonate.
作者信息
Gabard B, Planas-Bohne F, Regula G
出版信息
Toxicology. 1979 Mar-Apr;12(3):281-4. doi: 10.1016/0300-483x(79)90074-x.
PMID:494309
Abstract
Administration of various doses of the chelating agent 2,3-dimercaptopropane sodium sulfonate (Dimaval, DMPS) leads to a greatly enhanced excretion of Zn and Cu. The excretion of Co, Mn, Ni and Fe remains unchanged. The relevance of these findings to the toxicity of DMPS is discussed.
摘要
给予不同剂量的螯合剂2,3-二巯基丙烷磺酸钠（二巯丙磺钠，DMPS）会导致锌和铜的排泄量大幅增加。钴、锰、镍和铁的排泄量保持不变。文中讨论了这些发现与DMPS毒性的相关性。
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