Arnold W, Püschel K
Z Rechtsmed. 1979 Aug;83(3):265-72. doi: 10.1007/BF02333330.
Case report. A 82 year old woman died 80 min after accidental ingestion of 5 mg beta-methyl-digoxin. The autopsy and the histological examination revealed non-specific alterations due to shock and preexisting coronary heart disease. Digoxin levels in various fluids and tissues were estimated by radioimmunoassay: bloodplasma 20--25 ng/ml, liquor 10--13 ng/ml, liver 100--110 ng/g, kidney 130--145 ng/g; the gastric fluid contained 0,6 mg. Forensic aspects of glycosid-intoxication, especially of the varying concentrations in different tissues, are discussed.
病例报告。一名82岁女性在意外摄入5毫克β-甲基地高辛80分钟后死亡。尸检和组织学检查显示,死因是休克和先前存在的冠心病导致的非特异性改变。通过放射免疫分析法测定了各种体液和组织中的地高辛水平:血浆20 - 25纳克/毫升,脑脊液10 - 13纳克/毫升,肝脏100 - 110纳克/克,肾脏130 - 145纳克/克;胃液中含有0.6毫克。文中讨论了糖苷中毒的法医方面问题,特别是不同组织中浓度变化的情况。