McCormick K J, Stenback W A, Mumford D M, Trentin J J
Infect Immun. 1971 Jul;4(1):20-2. doi: 10.1128/iai.4.1.20-22.1971.
The complement-fixing (CF) activity of antigens from cultured Burkitt lymphoma cells was determined by using normal American sera as the source of antibody. Approximately 75% of the sera fixed complement with the positive cell lines. These lines contained the herpes-like virus detectable by electron microscopy. The content of CF antigen depended on the cell line used but appeared to be independent of the number of cells which produced Henle's immunofluorescence (IF) antigen. Only sera that reacted in the IF test also contained CF antibodies to the crude cell extracts.
通过使用正常美国血清作为抗体来源，测定了培养的伯基特淋巴瘤细胞抗原的补体结合（CF）活性。大约75%的血清能与阳性细胞系固定补体。这些细胞系含有通过电子显微镜可检测到的疱疹样病毒。CF抗原的含量取决于所使用的细胞系，但似乎与产生亨勒免疫荧光（IF）抗原的细胞数量无关。只有在IF试验中发生反应的血清才含有针对粗细胞提取物的CF抗体。
