Fauve R M, Dekaris D
Science. 1968 May 17;160(3829):795-6. doi: 10.1126/science.160.3829.795.
The capacity of peritoneal macrophages to spread was studied with cells of mice infected with Listeria monocytogenes and with cells of guinea pigs sensitized with BCG (bacille Calmette Guérin) vaccine or immunized with ovalbumin. In macrophages taken from animals having delayed hypersensitivity, this ability was markedly decreased by the presence of specific antigen for less than 1 hour. Such an effect was not observed in guinea pigs having only circulating antibodies.
利用感染单核细胞增生李斯特菌的小鼠细胞以及用卡介苗(Calmette - Guérin 杆菌)疫苗致敏或用卵清蛋白免疫的豚鼠细胞,研究了腹膜巨噬细胞的铺展能力。在取自具有迟发型超敏反应动物的巨噬细胞中,特异性抗原存在不到1小时,这种能力就会显著下降。在仅具有循环抗体的豚鼠中未观察到这种效应。