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脱氧核糖核酸抗体:一种检测其与脱氧核糖核酸主要相互作用的方法。

Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid.

作者信息

Wold R T, Young F E, Tan E M, Farr R S

出版信息

Science. 1968 Aug 23;161(3843):806-7. doi: 10.1126/science.161.3843.806.

DOI:10.1126/science.161.3843.806
PMID:4969617
Abstract

Antibody to DNA in human serums can be detected by the ammonium sulfate method. This sensitive and specific technique, which measures the primary interaction between DNA and antibody to DNA, is based on the observation that free DNA is soluble in 50-percent saturated ammonium sulfate whereas antibody-bound DNA is insoluble.

摘要

人血清中的DNA抗体可用硫酸铵法检测。这种灵敏且特异的技术用于测定DNA与DNA抗体之间的主要相互作用,其基于以下观察结果:游离DNA可溶于50%饱和度的硫酸铵,而与抗体结合的DNA则不溶。

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Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid.脱氧核糖核酸抗体:一种检测其与脱氧核糖核酸主要相互作用的方法。
Science. 1968 Aug 23;161(3843):806-7. doi: 10.1126/science.161.3843.806.
2
[Determination and importance of antibodies against deoxyribonucleic acid in the systemic lupus erythematosus].[系统性红斑狼疮中抗脱氧核糖核酸抗体的测定及其重要性]
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Measurement of serum DNA-binding activity in systemic lupus erythematosus.系统性红斑狼疮患者血清DNA结合活性的测定
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Antibodies to deoxyribonucleic acid irradiated with ultraviolet light: detection by precipitins and immunofluorescence.针对经紫外线照射的脱氧核糖核酸的抗体:通过沉淀素和免疫荧光法进行检测
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[Characteristics of the interaction of Klebsiella rhinoscleromatis DNA with the sera from patient with systemic lupus erythematos].鼻硬结克雷伯菌DNA与系统性红斑狼疮患者血清的相互作用特征
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Mutagenic action, loss of transforming activity, and inhibition of deoxyribonucleic acid template activity in vitro caused by chemical linkage of carcinogenic polycyclic hydrocarbons to deoxyribonucleic acid.致癌多环烃与脱氧核糖核酸发生化学连接后在体外引起的诱变作用、转化活性丧失及脱氧核糖核酸模板活性抑制。
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The substance with competence inducing activity interacts with DNA and produces a hyperchromic increase of optical density.具有活性诱导能力的物质与DNA相互作用,并导致光密度的增色增加。
Folia Microbiol (Praha). 1970;15(3):183-91. doi: 10.1007/BF02873082.
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Comparative study of antibodies to native and denatured DNA.天然DNA与变性DNA抗体的比较研究
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Character of anti-DNA antibodies in systemic lupus erythematosus.系统性红斑狼疮中抗DNA抗体的特征
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Serum DNA binding activity in healthy subjects and in rheumatic disease.健康受试者和风湿性疾病患者的血清DNA结合活性。
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An antibody profile of systemic lupus erythematosus detected by antigen microarray.抗原微阵列检测系统性红斑狼疮的抗体谱。
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Infliximab improves signs and symptoms of psoriatic arthritis: results of the IMPACT 2 trial.英夫利昔单抗可改善银屑病关节炎的体征和症状:IMPACT 2试验结果
Ann Rheum Dis. 2005 Aug;64(8):1150-7. doi: 10.1136/ard.2004.032268. Epub 2005 Jan 27.
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Psychiatric symptoms before systemic lupus erythematosus is diagnosed.系统性红斑狼疮确诊前的精神症状。
Rheumatol Int. 1994;14(2):57-62. doi: 10.1007/BF00300248.
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Clin Exp Immunol. 1995 Jul;101(1):55-9. doi: 10.1111/j.1365-2249.1995.tb02276.x.
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J Clin Pathol. 1980 May;33(5):488-92. doi: 10.1136/jcp.33.5.488.
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