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针对经紫外线照射的脱氧核糖核酸的抗体：通过沉淀素和免疫荧光法进行检测

Antibodies to deoxyribonucleic acid irradiated with ultraviolet light: detection by precipitins and immunofluorescence.

作者信息

Tan E M

出版信息

Science. 1968 Sep 27;161(3848):1353-4. doi: 10.1126/science.161.3848.1353.

DOI:10.1126/science.161.3848.1353
PMID:4970583
Abstract

Two rabbits were immunized with a complex consisting of ultravioietirradiated DNA and methylated bovine serum albumin. Serum antibodies reacted only with irradiated DNA, and the serological reaction was shown by immuneprecipitation and immunofluorescence.

摘要

用紫外线照射的DNA与甲基化牛血清白蛋白组成的复合物对两只兔子进行免疫。血清抗体仅与照射过的DNA发生反应，并且通过免疫沉淀和免疫荧光显示出血清学反应。

相似文献

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Antibodies to deoxyribonucleic acid irradiated with ultraviolet light: detection by precipitins and immunofluorescence.针对经紫外线照射的脱氧核糖核酸的抗体：通过沉淀素和免疫荧光法进行检测
Science. 1968 Sep 27;161(3848):1353-4. doi: 10.1126/science.161.3848.1353.
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Ultraviolet light alteration of cellular deoxyribonucleic acid in vivo.体内细胞脱氧核糖核酸的紫外线改变
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Specific binding of ribonucleic acid by antiadenosine antibodies.
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The occurrence and nature of precipitating antibodies in anti-DNA sera.抗DNA血清中沉淀抗体的出现及性质
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Precipitating antibodies to DNA induced by heat-denatured DNA-albumin conjugates in the rabbit.热变性DNA-白蛋白结合物在兔体内诱导产生的抗DNA沉淀抗体。
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引用本文的文献

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Antibodies to polynucleotides in human sera: antigenic specificity and relation to disease.人血清中多核苷酸抗体：抗原特异性及其与疾病的关系。
J Exp Med. 1971 Jul 1;134(1):294-312. doi: 10.1084/jem.134.1.294.
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The range and specificity of antinuclear antibodies in systemic lupus erythematosus.系统性红斑狼疮中抗核抗体的范围和特异性
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