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致病性奈瑟菌的细胞脂肪酸

Cellular fatty acids of pathogenic Neisseria.

作者信息

Moss C W, Kellogg D S, Farshy D C, Lambert M A, Thayer J D

出版信息

J Bacteriol. 1970 Oct;104(1):63-8. doi: 10.1128/jb.104.1.63-68.1970.

Abstract

The cellular fatty acid composition of 20 isolates of Neisseria gonorrhoeae and 21 isolates of N. meningitidis was examined by gas-liquid chromatography. Each isolate of the two species possessed similar fatty acid profiles which were characterized by five major acids, accounting for 80 to 85% of the total. The three most abundant acids in each species were palmitic, palmitoleic, and beta-hydroxylauric acids; lauric and myristic acids were the next most abundant. The presence of large amounts of beta-hydroxylauric acid (20% or greater) and the relative concentrations of the other four major acids appear to be useful markers for distinguishing N. gonorrhoeae and N. meningitidis fatty acids from those of other bacteria.

摘要

采用气液色谱法检测了20株淋病奈瑟菌和21株脑膜炎奈瑟菌的细胞脂肪酸组成。这两个菌种的每一株都具有相似的脂肪酸谱,其特征在于五种主要酸,占总量的80%至85%。每个菌种中含量最高的三种酸是棕榈酸、棕榈油酸和β-羟基月桂酸;月桂酸和肉豆蔻酸含量次之。大量β-羟基月桂酸(20%或更高)的存在以及其他四种主要酸的相对浓度似乎是区分淋病奈瑟菌和脑膜炎奈瑟菌脂肪酸与其他细菌脂肪酸的有用标志物。

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