频率脉冲电子捕获气液色谱法对淋巴细胞性脑膜炎的快速诊断：结核性、隐球菌性和病毒性脑膜炎的鉴别
Rapid diagnosis of lymphocytic meningitis by frequency-pulsed electron capture gas-liquid chromatography: differentiation of tuberculous, cryptococcal, and viral meningitis.
作者信息
Craven R B, Brooks J B, Edman D C, Converse J D, Greenlee J, Schlossberg D, Furlow T, Gwaltney J M, Miner W F
出版信息
J Clin Microbiol. 1977 Jul;6(1):27-32. doi: 10.1128/jcm.6.1.27-32.1977.
Abstract
Cerebrospinal fluid specimens from patients with tuberculous (17 cases), cryptococcal (15 cases), and viral (14 cases) meningitis were analyzed by frequency-pulsed electron capture gas-liquid chromatography and mass spectrometry. Compounds that disappeared after therapy were found to be present in each of these specimens and were not detected in controls. They occurred in repetitive patterns such that these three types of meningitis could be rapidly distinguished. The compound associated with tuberculous meningitis has been tentatively identified. These finding have implications for rapid diagnosis, pathophysiological studies, and possible new therapeutic approaches.
摘要
对结核性脑膜炎患者（17例）、隐球菌性脑膜炎患者（15例）和病毒性脑膜炎患者（14例）的脑脊液标本进行了频率脉冲电子捕获气液色谱和质谱分析。发现治疗后消失的化合物存在于上述每种标本中，而在对照标本中未检测到。它们以重复模式出现，从而可以快速区分这三种类型的脑膜炎。与结核性脑膜炎相关的化合物已初步鉴定。这些发现对快速诊断、病理生理学研究以及可能的新治疗方法具有重要意义。
相似文献
1
Rapid diagnosis of lymphocytic meningitis by frequency-pulsed electron capture gas-liquid chromatography: differentiation of tuberculous, cryptococcal, and viral meningitis.频率脉冲电子捕获气液色谱法对淋巴细胞性脑膜炎的快速诊断：结核性、隐球菌性和病毒性脑膜炎的鉴别
J Clin Microbiol. 1977 Jul;6(1):27-32. doi: 10.1128/jcm.6.1.27-32.1977.
2
Possibility of diagnosing meningitis by gas chromatography: cryptococcal meningitis.通过气相色谱法诊断脑膜炎的可能性：隐球菌性脑膜炎
J Clin Microbiol. 1976 Mar;3(3):239-45. doi: 10.1128/jcm.3.3.239-245.1976.
3
Electron capture gas chromatography detection and mass spectrum identification of 3-(2'-ketohexyl)indoline in spinal fluids of patients with tuberculous meningitis.结核性脑膜炎患者脑脊液中3-(2'-酮己基)吲哚啉的电子捕获气相色谱检测及质谱鉴定
J Clin Microbiol. 1977 Jun;5(6):625-8. doi: 10.1128/jcm.5.6.625-628.1977.
4
Cerebrospinal fluid indices in cryptococcal and tuberculous meningitis: the spider web coagulum and its diagnostic significance.隐球菌性脑膜炎和结核性脑膜炎的脑脊液指标：蛛网膜凝块及其诊断意义。
Mycoses. 1990 Jul-Aug;33(7-8):359-67. doi: 10.1111/myc.1990.33.7-8.359.
5
Frequency-pulsed electron capture gas-liquid chromatography and the tryptophan color test for rapid diagnosis of tuberculous and other forms of lymphocytic meningitis.频率脉冲电子捕获气液色谱法及色氨酸颜色试验用于快速诊断结核性及其他形式的淋巴细胞性脑膜炎。
J Clin Microbiol. 1980 Aug;12(2):208-15. doi: 10.1128/jcm.12.2.208-215.1980.
6
Rapid diagnosis of tuberculous meningitis by frequency-pulsed electron-capture gas-liquid chromatography detection of carboxylic acids in cerebrospinal fluid.通过频率脉冲电子捕获气液色谱法检测脑脊液中的羧酸快速诊断结核性脑膜炎
J Clin Microbiol. 1990 May;28(5):989-97. doi: 10.1128/jcm.28.5.989-997.1990.
7
[Significance of the determination of lactic acid in the cerebrospinal fluid for the differential diagnosis of meningitis].[脑脊液中乳酸测定对脑膜炎鉴别诊断的意义]
Pathol Biol (Paris). 1985 Apr;33(4):227-31.
8
[Meningitis and CSF cytology (author's transl)].[脑膜炎与脑脊液细胞学（作者译）]
Nervenarzt. 1979 Jan;50(1):5-9.
9
10
The diagnostic utility of the "Thwaites' system" and "lancet consensus scoring system" in tuberculous vs. non-tuberculous subacute and chronic meningitis: multicenter analysis of 395 adult patients.“Thwaites 系统”和“柳叶刀共识评分系统”在结核性与非结核性亚急性和慢性脑膜炎中的诊断效用：395 例成人患者的多中心分析。
BMC Infect Dis. 2020 Oct 23;20(1):788. doi: 10.1186/s12879-020-05502-9.
引用本文的文献
1
Management of central nervous system cryptococcosis.中枢神经系统隐球菌病的管理
West J Med. 1980 Feb;132(2):123-33.
2
Rapid differentiation of rocky mountain spotted fever from chickenpox, measles, and enterovirus infections and bacterial meningitis by frequency-pulsed electron capture gas-liquid chromatographic analysis of sera.通过血清的频率脉冲电子捕获气液色谱分析快速鉴别落基山斑疹热与水痘、麻疹、肠道病毒感染及细菌性脑膜炎。
J Clin Microbiol. 1981 Aug;14(2):165-72. doi: 10.1128/jcm.14.2.165-172.1981.
3
Frequency-pulsed electron capture gas-liquid chromatography and the tryptophan color test for rapid diagnosis of tuberculous and other forms of lymphocytic meningitis.频率脉冲电子捕获气液色谱法及色氨酸颜色试验用于快速诊断结核性及其他形式的淋巴细胞性脑膜炎。
J Clin Microbiol. 1980 Aug;12(2):208-15. doi: 10.1128/jcm.12.2.208-215.1980.
4
Rapid differentiation of the major causative agents of bacterial meningitis by use of frequency-pulsed electron capture gas-liquid chromatography: analysis of amines.使用频率脉冲电子捕获气液色谱法快速鉴别细菌性脑膜炎的主要病原体：胺类分析
J Clin Microbiol. 1980 Jan;11(1):52-8. doi: 10.1128/jcm.11.1.52-58.1980.
5
Rapid differentiation of the major causative agents of bacterial meningitis by use of frequency-pulsed electron capture gas-liquid chromatograph: analysis of acids.利用频率脉冲电子捕获气液色谱法快速鉴别细菌性脑膜炎的主要病原体：酸分析
J Clin Microbiol. 1980 Jan;11(1):45-51. doi: 10.1128/jcm.11.1.45-51.1980.
6
Evaluation of adenosine deaminase activity and antibody to Mycobacterium tuberculosis antigen 5 in cerebrospinal fluid and the radioactive bromide partition test for the early diagnosis of tuberculosis meningitis.脑脊液中腺苷脱氨酶活性及结核分枝杆菌抗原5抗体的评估以及放射性溴化物分配试验在结核性脑膜炎早期诊断中的应用
Arch Dis Child. 1986 May;61(5):428-35. doi: 10.1136/adc.61.5.428.
7
Applications of cellular fatty acid analysis.细胞脂肪酸分析的应用
Clin Microbiol Rev. 1991 Oct;4(4):422-38. doi: 10.1128/CMR.4.4.422.
8
Laboratory diagnosis of bacterial meningitis.细菌性脑膜炎的实验室诊断
Clin Microbiol Rev. 1992 Apr;5(2):130-45. doi: 10.1128/CMR.5.2.130.
9
Electron capture gas-liquid chromatographic study of metabolites produced by some arthritic transudate-associated organisms in vitro and in vivo in rabbit models.电子捕获气液色谱法对兔模型体内外某些与关节炎渗出液相关生物产生的代谢产物的研究。
J Clin Microbiol. 1978 Oct;8(4):402-9. doi: 10.1128/jcm.8.4.402-409.1978.
10
Possible use of frequency-pulse-modulated electron capture gas-liquid chromatography to identify septic and aseptic causes of pleural effusions.频率脉冲调制电子捕获气液色谱法在鉴别胸腔积液感染性与非感染性病因中的可能应用。
J Clin Microbiol. 1978 Aug;8(2):203-8. doi: 10.1128/jcm.8.2.203-208.1978.
本文引用的文献
1
Ultrasensitive detection of certain microbial metabolites by gas chromatography.气相色谱法对某些微生物代谢产物的超灵敏检测
Anal Biochem. 1967 Sep;20(3):548-50. doi: 10.1016/0003-2697(67)90300-4.
2
The role of gas chromatography in the clinical microbiology laboratory.气相色谱法在临床微生物学实验室中的作用。
J Infect Dis. 1969 Jun;119(6):658-62. doi: 10.1093/infdis/119.6.658.
3
Characterization of the C15 branched-chain fatty acids of Corynebacterium acnes by gas chromatography.通过气相色谱法对痤疮丙酸杆菌的C15支链脂肪酸进行表征。
J Bacteriol. 1968 Jan;95(1):241-2. doi: 10.1128/jb.95.1.241-242.1968.
4
Differentiation between Clostridium sordellii and Clostridi- um bifermentans by gas chromatography.通过气相色谱法鉴别索氏梭菌和双酶梭菌。
J Bacteriol. 1969 Oct;100(1):528-30. doi: 10.1128/jb.100.1.528-530.1969.
5
Analysis by gas chromatography of fatty acids found in whole cultural extracts of Neisseria species.通过气相色谱法对淋病奈瑟菌全培养提取物中发现的脂肪酸进行分析。
Can J Microbiol. 1971 Apr;17(4):531-43. doi: 10.1139/m71-088.
6
Reaction of nitrosamine with fluorinated anhydrides and pyridine to form electron capturing derivatives.亚硝胺与氟化酸酐和吡啶反应形成电子捕获衍生物。
Anal Chem. 1972 Sep;44(13):1881-6. doi: 10.1021/ac60319a058.
7
Cellular fatty acids of pathogenic Neisseria.致病性奈瑟菌的细胞脂肪酸
J Bacteriol. 1970 Oct;104(1):63-8. doi: 10.1128/jb.104.1.63-68.1970.
8
Rapid diagnosis of infection by gas-liquid chromatography: analysis of sugars in normal and infected cerebrospinal fluid.通过气液色谱法快速诊断感染：正常和感染脑脊液中糖的分析
Appl Microbiol. 1974 Aug;28(2):298-302. doi: 10.1128/am.28.2.298-302.1974.
9
Comparison of rapid methods for analysis of bacterial fatty acids.细菌脂肪酸分析快速方法的比较
Appl Microbiol. 1974 Jul;28(1):80-5. doi: 10.1128/am.28.1.80-85.1974.
10
Production of glutaric acid: a useful criterion for differentiating Pseudomonas diminuta from Pseudomonas vesiculare.戊二酸的产生：区分微小假单胞菌和泡囊假单胞菌的一个有用标准。
Appl Microbiol. 1974 Feb;27(2):437-9. doi: 10.1128/am.27.2.437-439.1974.
Zotero 插件