与慢性淋巴细胞白血病患者血浆微粒部分相关的脱氧核糖核酸聚合酶活性
Deoxyribonucleic acid polymerase activity associated with a plasma particulate fraction from patients with chronic lymphocytic leukemia.
作者信息
Kiessling A A, Weber G H, Deeney A O, Possehl E A, Beaudreau G S
出版信息
J Virol. 1971 Feb;7(2):221-6. doi: 10.1128/JVI.7.2.221-226.1971.
Abstract
Plasma from two cases of chronic lymphocytic leukemia have been examined for deoxyribonucleic acid (DNA) polymerase activity. In both cases, detectable enzyme activity was present. In the plasma from a patient known to have chronic lymphocytic leukemia for 10 years, the enzyme activity was sufficiently high to study product formation, buoyant density of the enzyme activity, deoxyribonucleoside triphosphate requirements, and kinetics of DNA synthesis. These studies are presented in this report.
摘要
已对两例慢性淋巴细胞白血病患者的血浆进行了脱氧核糖核酸（DNA）聚合酶活性检测。在这两例患者中均检测到了酶活性。在一名已知患慢性淋巴细胞白血病10年的患者血浆中，酶活性高到足以研究产物形成、酶活性的浮力密度、脱氧核苷三磷酸需求以及DNA合成动力学。本报告展示了这些研究。
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