Hatanaka M, Huebner R J, Gilden R V
Proc Natl Acad Sci U S A. 1970 Sep;67(1):143-7. doi: 10.1073/pnas.67.1.143.
C-type RNA viruses, originating in mouse, cat, hamster, and viper, catalyze the synthesis of DNA from its constituent deoxyribonucleoside triphosphates. Both the rate and extent of the reaction were significantly enhanced by brief treatment of the intact virus with ether. A proportion of the newly synthesized DNA was associated with virions when intact virus was used as template; this was not the case with ether-treated virus. In both cases, DNA extracted from the reaction mixture sedimented slowly, at about 2-4 S.
源自小鼠、猫、仓鼠和蝰蛇的C型RNA病毒，催化由其组成的脱氧核糖核苷三磷酸合成DNA。用乙醚对完整病毒进行短暂处理可显著提高反应的速率和程度。当使用完整病毒作为模板时，新合成的DNA有一部分与病毒粒子相关联；而经乙醚处理的病毒则并非如此。在这两种情况下，从反应混合物中提取的DNA沉降缓慢，约为2 - 4 S。
