Weise M, Voller A
Tropenmed Parasitol. 1975 Dec;26(4):390-4.
This paper describes the characterization of proteinuria in Aotus monkeys infected with quartan malaria (Plasmodium brasilianum), using a micro-disc-electrophoresis system. In the post infection urine samples, increases in total proteinuria, albuminuria and gamma-globulinuria were noted a few weeks after peak parasitaemia. Two new proteins also appeared in the urine of malaria infected animals. These findings are discussed with reference to the belief that the Aotus-P. brasilianum system can be a model for human malaria in renal immunopathology.
本文描述了使用微盘电泳系统对感染三日疟(巴西疟原虫)的夜猴蛋白尿特征的研究。在感染后的尿液样本中,发现在寄生虫血症高峰几周后,总蛋白尿、白蛋白尿和γ-球蛋白尿增加。在感染疟疾动物的尿液中还出现了两种新蛋白质。参照夜猴-巴西疟原虫系统可作为人类疟疾肾脏免疫病理学模型这一观点,对这些发现进行了讨论。