5-碘脱氧尿苷和二甲基亚砜对人类肿瘤中病毒的激活作用。
Activation of viruses in human tumors by 5-iododeoxyuridine and dimethyl sulfoxide.
作者信息
Stewart S E, Kasnic G, Draycott C, Ben T
出版信息
Science. 1972 Jan 14;175(4018):198-9. doi: 10.1126/science.175.4018.198.
PMID:5008440
Abstract
Dimethyl sulfoxide added to cultures first treated with 5-iododeoxyuridine increased C-type virus production approximately tenfold in a human rhabdomyosarcoma cell line. 5-Iododeoxyuridine followed by dimethyl sulfoxide also activated a similar C-type virus in a metastatic tumor from a bronchial node taken from a 52-year-old male.
摘要
添加到先用5-碘脱氧尿苷处理过的培养物中的二甲基亚砜，使一种人横纹肌肉瘤细胞系中的C型病毒产量增加了约十倍。先用5-碘脱氧尿苷处理，再用二甲基亚砜处理，也激活了一名52岁男性支气管淋巴结转移性肿瘤中类似的C型病毒。
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