小鼠脑池内 A 型颗粒无法与内质网的膜分离。
Murine intracisternal A type particles fail to separate from the membrane of the endoplasmic reticulum.
作者信息
Perk K, Dahlberg J E
出版信息
J Virol. 1974 Nov;14(5):1304-6. doi: 10.1128/JVI.14.5.1304-1306.1974.
Abstract
Analysis of serial sections of murine cells containing intracisternal A particles revealed that over 99% of all A particles remain in a budding configuration. This indicates that these particles fail to detach from the membrane of the endoplasmic reticulum. This observation explains how, despite their intracellular abundance in certain murine tumors, no extracellular A-type particles can be found.
摘要
对含有核内池A颗粒的鼠细胞连续切片进行分析发现，所有A颗粒中超过99%仍处于出芽状态。这表明这些颗粒未能从内质网的膜上脱离。这一观察结果解释了为什么尽管在某些鼠肿瘤中它们在细胞内大量存在，但却找不到细胞外A型颗粒。
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