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肥皂腔室试验。一种评估肥皂刺激性的新方法。

The soap chamber test. A new method for assessing the irritancy of soaps.

作者信息

Frosch P J, Kligman A M

出版信息

J Am Acad Dermatol. 1979 Jul;1(1):35-41. doi: 10.1016/s0190-9622(79)70001-6.

Abstract

The chamber test for assessing the irritancy of soaps entails five weekday exposures to 8% solutions with readings of scaling, redness, and fissuring on the following Monday. Eighteen well-known toilet soaps were evaluated. Great differences were noted. Most had an appreciable irritancy potential. These results contrast with a number of studies which failed to show differences among soaps or which concluded that soaps were innocuous.

摘要

评估肥皂刺激性的试验要求在工作日期间将皮肤暴露于8%的溶液中5次,并在接下来的周一观察皮肤脱屑、发红和皲裂情况。对18种知名香皂进行了评估。结果显示出巨大差异。大多数香皂都有相当大的潜在刺激性。这些结果与一些研究形成对比,那些研究未能显示出不同肥皂之间的差异,或者得出肥皂无害的结论。

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