• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

血小板中膜系统的相互作用。

Interaction of membrane systems in blood platelets.

作者信息

White J G

出版信息

Am J Pathol. 1972 Feb;66(2):295-312.

PMID:5009975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2032496/
Abstract

The existence of two separate groups of membrane-enclosed channels in platelets, the open canalicular system (OCS) and the dense tubular system (DTS), has been recognized for several years. The present study has employed ultrastructural observations on normal platelets, cells from a child with the gray platelet syndrome and cytochemical localization of peroxidase in platelets to define the origin of the DTS and point out a specialized membrane complex in platelets formed by interaction of channels from the OCS and DTS. The similarities of membrane complexes in platelets to the organization of membrane systems in muscle is pointed out, and their potential function as the sarcoplasmic reticulum of platelets is discussed.

摘要

血小板中存在两组独立的膜封闭通道,即开放管道系统(OCS)和致密管道系统(DTS),这一现象已被认识多年。本研究通过对正常血小板、一名患有灰色血小板综合征儿童的细胞进行超微结构观察,以及对血小板中过氧化物酶进行细胞化学定位,来确定DTS的起源,并指出血小板中由OCS和DTS通道相互作用形成的一种特殊膜复合体。文中指出了血小板中膜复合体与肌肉膜系统组织的相似性,并讨论了它们作为血小板肌浆网的潜在功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/1508dd0c9bce/amjpathol00550-0121-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/af298a9dd4f5/amjpathol00550-0122-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/fce33a64a6d5/amjpathol00550-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/4afcd2820fa6/amjpathol00550-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/2d5c7a7a076a/amjpathol00550-0119-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/1508dd0c9bce/amjpathol00550-0121-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/af298a9dd4f5/amjpathol00550-0122-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/fce33a64a6d5/amjpathol00550-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/4afcd2820fa6/amjpathol00550-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/2d5c7a7a076a/amjpathol00550-0119-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ac/2032496/1508dd0c9bce/amjpathol00550-0121-a.jpg

相似文献

1
Interaction of membrane systems in blood platelets.血小板中膜系统的相互作用。
Am J Pathol. 1972 Feb;66(2):295-312.
2
Electron microscopic and cytochemical observations on the membrane systems of the chicken thrombocyte.鸡血小板膜系统的电子显微镜和细胞化学观察
J Anat. 1978 Jan;125(Pt 1):11-21.
3
Ultrastructural localization of peroxidase activity in human platelets and megakaryocytes.人血小板和巨核细胞中过氧化物酶活性的超微结构定位
Am J Pathol. 1972 Feb;66(2):277-93.
4
Disruption of microtubules in vivo by vincristine induces large membrane complexes and other cytoplasmic abnormalities in megakaryocytes and platelets of normal rats like those in human and Wistar Furth rat hereditary macrothrombocytopenias.长春新碱在体内破坏微管会在正常大鼠的巨核细胞和血小板中诱导出大的膜复合物和其他细胞质异常,类似于人类和威斯塔·富思大鼠遗传性大血小板减少症中的情况。
J Cell Physiol. 1995 Jan;162(1):86-102. doi: 10.1002/jcp.1041620111.
5
The surface-connected canalicular system of blood platelets--a fenestrated membrane system.血小板的表面连接小管系统——一种有窗孔的膜系统。
Am J Pathol. 1980 Nov;101(2):353-64.
6
Effects of large latex particle uptake of the surface connected canalicular system of blood platelets: a freeze-fracture and cytochemical study.血小板表面连接小管系统摄取大乳胶颗粒的效应:一项冷冻蚀刻和细胞化学研究。
Ultrastruct Pathol. 1981 Jul-Sep;2(3):277-87. doi: 10.3109/01913128109048311.
7
Platelet pathology in carriers of the X-linked GATA-1 macrothrombocytopenia.X连锁GATA-1大血小板减少症携带者的血小板病理学
Platelets. 2007 Dec;18(8):620-7. doi: 10.1080/09537100701655384.
8
[Improved methods for the cytochemical demonstration of platelet peroxidase (author's transl)].血小板过氧化物酶细胞化学显示的改良方法(作者译)
Nouv Rev Fr Hematol (1978). 1976;16(3):381-9.
9
Platelet pathology in sex-linked GATA-1 dyserythropoietic macrothrombocytopenia II. Cytochemistry.性连锁GATA-1异常红细胞生成性大血小板减少症II中的血小板病理学。细胞化学。
Platelets. 2007 Sep;18(6):436-50. doi: 10.1080/09537100701280662.
10
Localization of a lysosomal enzyme in platelets from patients with the White platelet syndrome.白色血小板综合征患者血小板中溶酶体酶的定位
Platelets. 2006 Jun;17(4):231-49. doi: 10.1080/09537100500468013.

引用本文的文献

1
Role of heat shock protein 47 in platelet glycoprotein VI dimerization and signaling.热休克蛋白47在血小板糖蛋白VI二聚化及信号传导中的作用
Res Pract Thromb Haemost. 2023 Aug 23;7(6):102177. doi: 10.1016/j.rpth.2023.102177. eCollection 2023 Aug.
2
Megapinosomes and homologous structures in hematopoietic cells.巨核细胞包涵体和造血细胞中的同源结构。
Histochem Cell Biol. 2022 Sep;158(3):253-260. doi: 10.1007/s00418-022-02124-x. Epub 2022 Jul 12.
3
Super-resolution imaging of platelet-activation process and its quantitative analysis.

本文引用的文献

1
THE PLATELET-FIBRIN RELATIONSHIP IN HUMAN BLOOD CLOTS: AN ULTRASTRUCTURAL STUDY UTILIZING FERRITIN-CONJUGATED ANTI-HUMAN FIBRINOGEN ANTIBODY.人血凝块中血小板与纤维蛋白的关系:一项利用铁蛋白偶联抗人纤维蛋白原抗体的超微结构研究。
Blood. 1965 Feb;25:241-57.
2
THE EFFECT OF INCUBATION AND STORAGE ON HUMAN PLATELET STRUCTURE AS STUDIED BY ELECTRON MICROSCOPY.电子显微镜研究孵育和储存对人血小板结构的影响
Blood. 1965 Mar;25:345-55.
3
The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.
血小板活化过程的超分辨成像及其定量分析。
Sci Rep. 2021 May 18;11(1):10511. doi: 10.1038/s41598-021-89799-9.
4
Nicergoline inhibits human platelet Ca(2+) signalling through triggering a microtubule-dependent reorganization of the platelet ultrastructure.尼麦角林通过引发血小板超微结构的微管依赖性重组来抑制人血小板Ca(2+)信号传导。
Br J Pharmacol. 2016 Jan;173(1):234-47. doi: 10.1111/bph.13361. Epub 2015 Dec 5.
5
Overview of platelet physiology: its hemostatic and nonhemostatic role in disease pathogenesis.血小板生理学概述:其在疾病发病机制中的止血和非止血作用
ScientificWorldJournal. 2014 Mar 3;2014:781857. doi: 10.1155/2014/781857. eCollection 2014.
6
Platelets and cancer: a casual or causal relationship: revisited.血小板与癌症:偶然还是因果关系:再探讨
Cancer Metastasis Rev. 2014 Mar;33(1):231-69. doi: 10.1007/s10555-014-9498-0.
7
Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets.细胞周围Ca(2+)循环增强人血小板中凝血酶诱发的Ca(2+)信号。
Physiol Rep. 2013 Oct;1(5):e00085. doi: 10.1002/phy2.85. Epub 2013 Oct 11.
8
Rapid ultrastructural detection of success or failure after bone marrow transplantation in the Chediak-Higashi syndrome.骨髓移植后 Chediak-Higashi 综合征成功或失败的快速超微结构检测。
Platelets. 2013;24(1):71-4. doi: 10.3109/09537104.2011.654293. Epub 2012 Jun 27.
9
Blood-nanoparticle interactions and in vivo biodistribution: impact of surface PEG and ligand properties.血液-纳米颗粒相互作用及体内生物分布:表面聚乙二醇和配体性质的影响
Mol Pharm. 2012 Aug 6;9(8):2146-55. doi: 10.1021/mp200626j. Epub 2012 Jul 23.
10
The York Platelet Syndrome: a third case.约克血小板综合征:第三例报告。
Platelets. 2011;22(2):117-34. doi: 10.3109/09537104.2010.524323. Epub 2010 Nov 30.
注入的辣根过氧化物酶在小鼠肾近端小管吸收的早期阶段:一种新技术的超微结构细胞化学研究
J Histochem Cytochem. 1966 Apr;14(4):291-302. doi: 10.1177/14.4.291.
4
Further studies on microtubules. A marginal bundle in human and rat thrombocytes.微管的进一步研究。人和大鼠血小板中的边缘束。
J Ultrastruct Res. 1965 Dec;13(5):469-77. doi: 10.1016/s0022-5320(65)90009-2.
5
The submembrane filaments of blood platelets.血小板的膜下细丝。
Am J Pathol. 1969 Aug;56(2):267-77.
6
Effects of colchicine and vinca alkaloids on human platelets. II. Changes in the dense tubular system and formation of an unusual inclusion in incubated cells.秋水仙碱和长春花生物碱对人血小板的作用。II. 致密管状系统的变化及孵育细胞中异常包涵体的形成。
Am J Pathol. 1968 Sep;53(3):447-61.
7
The transfer of thorium particles from plasma to platelets and platelet granules.钍颗粒从血浆向血小板及血小板颗粒的转移。
Am J Pathol. 1968 Oct;53(4):567-75.
8
Localization of endogenous peroxidase in rat exorbital lacrimal gland.大鼠眶外泪腺内源性过氧化物酶的定位
J Histochem Cytochem. 1971 Apr;19(4):216-25. doi: 10.1177/19.4.216.
9
New observations on microbodies. A cytochemical study on CPIB-treated rat liver.关于微体的新观察。对CPIB处理的大鼠肝脏的细胞化学研究。
J Cell Biol. 1970 Apr;45(1):118-29. doi: 10.1083/jcb.45.1.118.
10
Heterogeneity of human platelets. Metabolic and kinetic evidence suggestive of young and old platelets.人类血小板的异质性。代谢和动力学证据表明存在年轻血小板和衰老血小板。
Ser Haematol. 1971;4(1):75-97.