地高辛对人体红细胞电解质的影响。
Effect of digoxin on human red blood cell electrolytes.
作者信息
Kettlewell M, Nowers A, White R
出版信息
Br J Pharmacol. 1972 Jan;44(1):165-7. doi: 10.1111/j.1476-5381.1972.tb07250.x.
Abstract
Red blood cell electrolytes were measured during 48 h after administration of digoxin to twelve patients. The concentrations of some red cell electrolytes changed: sodium increased while potassium decreased significantly. These findings agree with in vitro experiments on red cells and other tissues including myocardium. Change in membrane ATPase activity is probably responsible for the electrolyte changes both in vitro and in vivo.
摘要
在给12名患者服用地高辛后的48小时内测量了红细胞电解质。一些红细胞电解质的浓度发生了变化：钠增加而钾显著减少。这些发现与对红细胞及包括心肌在内的其他组织的体外实验结果一致。膜ATP酶活性的变化可能是体外和体内电解质变化的原因。
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引用本文的文献
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2
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