Boxer R J, Waisman J, Lieber M M, Mampaso F M, Skinner D G
J Urol. 1979 Nov;122(5):598-601. doi: 10.1016/s0022-5347(17)56521-0.
We submitted to computer analysis 109 items of pathologic, clinical and survival data from 96 patients with renal carcinoma treated by nephrectomy with or without adjuvant therapy between 1956 and 1976. The combined 1, 5 and 10-year calculated survival rates for potentially curable non-metastatic renal carcinoma (stages I, II and III, provided the regional lymph nodes were not involved) were 95, 61 and 47 per cent, respectively, compared to 1, 5 and 10-year survival rates of 61, 5 and 0 per cent, respectively, for stage IV tumors. The cytoplasmic appearance (clear or granular) was not a significant microscopic feature relevant to survival of the patient but the grade of the tumor was predictive of the outcome of disease. Other features of renal carcinoma, particularly invasion of the renal vein and, to a lesser degree, perinephric fat, were not as prognostically significant in this series. In this retrospective study we further analyze the clinical, radiologic, pathologic and survival data of this group of patients.
我们将1956年至1976年间接受肾切除术（无论有无辅助治疗）的96例肾癌患者的109项病理、临床和生存数据进行了计算机分析。对于潜在可治愈的非转移性肾癌（I、II和III期，前提是区域淋巴结未受累），计算得出的1年、5年和10年联合生存率分别为95%、61%和47%，而IV期肿瘤的1年、5年和10年生存率分别为61%、5%和0%。细胞质外观（透明或颗粒状）并非与患者生存相关的显著微观特征，但肿瘤分级可预测疾病转归。肾癌的其他特征，特别是肾静脉侵犯以及程度较轻的肾周脂肪侵犯，在本系列研究中预后意义不大。在这项回顾性研究中，我们进一步分析了该组患者的临床、放射学、病理和生存数据。
