前列腺素B1的聚合物衍生物PGBX对小鼠遗传性糖尿病正常化的剂量依赖性。
Dose dependence of PGBX, a polymeric derivative of prostaglandin B1, for normalization of hereditary diabetes of the mouse.
作者信息
Polis B D, Polis E
出版信息
Physiol Chem Phys. 1979;11(1):3-8.
PMID:504362
Abstract
A polymeric derivative of prostaglandin B1, PGBX, which reactivates phosphorylation in damaged mitochondria, is shown to normalize the high blood glucose, obesity, and excessive appetite of the hereditary diabetic mouse. The degree of normalization is shown to vary with dosage.
摘要
前列腺素B1的一种聚合物衍生物PGBX，可使受损线粒体中的磷酸化重新激活，已证明它能使遗传性糖尿病小鼠的高血糖、肥胖和食欲过盛恢复正常。恢复正常的程度显示会随剂量而变化。
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