Kono S, Ikeda M
Br J Cancer. 1979 Sep;40(3):449-55. doi: 10.1038/bjc.1979.200.
Geographical correlations between standardized, mortality ratios (SMRs) of cancers and consumption of different types of alcoholic beverages (saké synthetic saké, shochu, beer, wine, and whisky), of cigarettes, and urbanization were examined for all 46 prefectures in Japan. Suggestive correlations were observed between cancer of the oesophagus in males and both shochu and whisky (r = 0.27 and 0.22 respectively), between cancer of the rectum in males and wine (r = 0.45), and between cancer of the prostate and shochu (r = 0.50). These correlations were also confirmed in the partial correlations between SMRs of cancers and consumption of alcoholic beverages, controlling for the two variables urbanization and consumption of cigarettes. Alhtough cancers of other sites were also correlated with certain types of alcoholic beverages, their associations seemed to be secondary to other factors. The validity of higher-order partial correlations and the problems of correlation study are also referred to.
对日本46个都道府县的癌症标准化死亡率(SMR)与不同类型酒精饮料(清酒、合成清酒、烧酒、啤酒、葡萄酒和威士忌)、香烟消费以及城市化之间的地理相关性进行了研究。观察到男性食管癌与烧酒和威士忌之间存在提示性相关性(分别为r = 0.27和0.22),男性直肠癌与葡萄酒之间存在相关性(r = 0.45),前列腺癌与烧酒之间存在相关性(r = 0.50)。在控制城市化和香烟消费这两个变量的情况下,癌症SMR与酒精饮料消费之间的偏相关性也证实了这些相关性。尽管其他部位的癌症也与某些类型的酒精饮料相关,但其关联似乎是由其他因素导致的。还提到了高阶偏相关性的有效性以及相关性研究的问题。