Effect of chronic N,N-diethylnitrosamine on the excision of O6-ethylguanine from rat liver DNA.
作者信息
Margison G P, Curtin N J, Snell K, Craig A W
出版信息
Br J Cancer. 1979 Nov;40(5):809-13. doi: 10.1038/bjc.1979.266.
Abstract
摘要
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Effect of chronic N,N-diethylnitrosamine on the excision of O6-ethylguanine from rat liver DNA.慢性N，N-二乙基亚硝胺对大鼠肝脏DNA中O6-乙基鸟嘌呤切除的影响。
Br J Cancer. 1979 Nov;40(5):809-13. doi: 10.1038/bjc.1979.266.
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Effect of chronic administration of dimethylnitrosamine on the excision of O6-methylguanine from rat liver DNA.长期给予二甲基亚硝胺对大鼠肝脏DNA中O6-甲基鸟嘌呤切除的影响。
Cancer Lett. 1976 Nov;2(2):79-85. doi: 10.1016/s0304-3835(76)80015-8.
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[Alkylation of liver DNA purines in rats of different age treated with diethylnitrosamine].[用二乙基亚硝胺处理的不同年龄大鼠肝脏DNA嘌呤的烷基化作用]
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[Effect of molybdenum Mo on the alkylation of DNA in the liver of rats treated with 14C-diethylnitrosamine].[钼（Mo）对用¹⁴C-二乙基亚硝胺处理的大鼠肝脏中DNA烷基化的影响]
Zhonghua Zhong Liu Za Zhi. 1987 Jan;9(1):21-4.
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Kinetics of formation of O6-ethylguanine in, and its removal from liver DNA of rats receiving diethylnitrosamine.接受二乙基亚硝胺的大鼠肝脏DNA中O6-乙基鸟嘌呤的形成动力学及其从肝脏DNA中的去除
Chem Biol Interact. 1977 Oct;19(1):1-11. doi: 10.1016/0009-2797(77)90038-2.
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Formation and persistence of ethylguanines in liver DNA of rainbow trout (Salmo gairdneri) treated with diethylnitrosamine by water exposure.经水暴露用二乙基亚硝胺处理的虹鳟（Salmo gairdneri）肝脏DNA中乙基鸟嘌呤的形成与持久性。
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Action of phenobarbital given to rats together with diethylnitrosamine on the O6-ethylguanine content of liver DNA.给大鼠注射苯巴比妥与二乙基亚硝胺后对肝脏DNA中O6-乙基鸟嘌呤含量的影响。
Eur J Cancer Clin Oncol. 1988 Jul;24(7):1117-21. doi: 10.1016/0277-5379(88)90117-4.
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Enhanced repair of O6-methylguanine in liver DNA of rats pretreated with phenobarbital, 2,3,7,8-tetrachlorodibenzo-p-dioxin, ethionine, or N-alkyl-N-nitrosoureas.用苯巴比妥、2,3,7,8-四氯二苯并对二恶英、乙硫氨酸或N-烷基-N-亚硝基脲预处理的大鼠肝脏DNA中O6-甲基鸟嘌呤修复增强。
Carcinogenesis. 1986 Dec;7(12):1941-7. doi: 10.1093/carcin/7.12.1941.
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Effect of partial hepatectomy on removal of O6-methylguanine from alkylated DNA by rat liver extracts.部分肝切除对大鼠肝脏提取物从烷基化DNA中去除O6-甲基鸟嘌呤的影响。
Biochem J. 1981 Jul 1;197(1):195-201. doi: 10.1042/bj1970195.
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Interaction of chemical carcinogens with macromolecules.化学致癌物与大分子的相互作用。
J Cancer Res Clin Oncol. 1981;99(1-2):167-86. doi: 10.1007/BF00412452.
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Adaptive increase of O6-methylguanine-acceptor protein in HeLa cells following N-methyl-N'-nitro-N-nitrosoguanidine treatment.经N-甲基-N'-硝基-N-亚硝基胍处理后，HeLa细胞中O6-甲基鸟嘌呤受体蛋白的适应性增加。
Nucleic Acids Res. 1982 Aug 11;10(15):4595-604. doi: 10.1093/nar/10.15.4595.
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Cell-specific differences in O6-alkylguanine DNA repair activity during continuous exposure to carcinogen.持续暴露于致癌物期间O6-烷基鸟嘌呤DNA修复活性的细胞特异性差异。
Proc Natl Acad Sci U S A. 1982 Sep;79(18):5499-502. doi: 10.1073/pnas.79.18.5499.
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Repair of O6-methylguanine in rat liver DNA is enhanced by pretreatment with single or multiple doses of aflatoxin B1.用单剂量或多剂量黄曲霉毒素B1预处理可增强大鼠肝脏DNA中O6-甲基鸟嘌呤的修复。
Br J Cancer. 1981 Jun;43(6):850-5. doi: 10.1038/bjc.1981.124.
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O6-methylguanine repair in liver cells in vivo: comparison between G1- and S-phase of the cell cycle.体内肝细胞中的O6-甲基鸟嘌呤修复：细胞周期G1期和S期之间的比较
J Cancer Res Clin Oncol. 1984;108(1):36-45. doi: 10.1007/BF00390971.
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O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine.在持续接触二乙基亚硝胺的大鼠肝细胞DNA中，O4-乙基脱氧胸苷会累积，而O6-乙基脱氧鸟苷则不会。
Proc Natl Acad Sci U S A. 1984 Mar;81(6):1692-5. doi: 10.1073/pnas.81.6.1692.
本文引用的文献
1
Possible relevance of O-6 alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides.脱氧鸟苷的O-6烷基化与亚硝胺和亚硝酰胺的致突变性和致癌性之间可能存在的关联。
Nature. 1969 Jul 12;223(5202):206-7. doi: 10.1038/223206a0.
2
The properties of O 6 -methylguanine in templates for RNA polymerase.RNA聚合酶模板中O 6 -甲基鸟嘌呤的特性。
Biochim Biophys Acta. 1973 May 10;308(2):310-6. doi: 10.1016/0005-2787(73)90160-3.
3
Persistence of O6-ethylguanine in rat-brain DNA: correlation with nervous system-specific carcinogenesis by ethylnitrosourea.大鼠脑DNA中O6-乙基鸟嘌呤的持久性：与乙基亚硝基脲诱导的神经系统特异性致癌作用的相关性。
Proc Natl Acad Sci U S A. 1974 Mar;71(3):639-43. doi: 10.1073/pnas.71.3.639.
4
Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.N-甲基-N-亚硝基脲的致癌性：DNA中O6-甲基鸟嘌呤切除修复的可能作用。
J Natl Cancer Inst. 1974 Dec;53(6):1839-41.
5
6
Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA.
Nature. 1975 Mar 20;254(5497):261-2. doi: 10.1038/254261a0.
7
Methylated purines in the deoxyribonucleic acid of various Syrian-golden-hamster tissues after administration of a hepatocarcinogenic dose of dimethylnitrosamine.给予致癌剂量的二甲基亚硝胺后，叙利亚金仓鼠各种组织的脱氧核糖核酸中的甲基化嘌呤。
Biochem J. 1976 Sep 1;157(3):627-34. doi: 10.1042/bj1570627.
8
Kinetics of formation of O6-ethylguanine in, and its removal from liver DNA of rats receiving diethylnitrosamine.接受二乙基亚硝胺的大鼠肝脏DNA中O6-乙基鸟嘌呤的形成动力学及其从肝脏DNA中的去除
Chem Biol Interact. 1977 Oct;19(1):1-11. doi: 10.1016/0009-2797(77)90038-2.
9
Effect of pretreatment with other dialkylnitrosamines on excision from hepatic DNA of O6-methylguanine produced by dimethylnitrosamine.其他二烷基亚硝胺预处理对二甲基亚硝胺所致肝DNA中O6-甲基鸟嘌呤切除的影响。
Chem Biol Interact. 1978 Jul;22(1):109-16. doi: 10.1016/0009-2797(78)90154-0.
10
In vivo alkylation of foetal, maternal and normal rat tissue nucleic acids by 3-methyl-1-phenyltriazene.3-甲基-1-苯基三氮烯对胎儿、母体及正常大鼠组织核酸的体内烷基化作用
Chem Biol Interact. 1979 May;25(2-3):345-53. doi: 10.1016/0009-2797(79)90056-5.
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