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Blood-group precursors and cancer-related antigens.

作者信息

Feizi T, Turberville C, Westwood J H

出版信息

Lancet. 1975 Aug 30;2(7931):391-3. doi: 10.1016/s0140-6736(75)92899-8.

DOI:10.1016/s0140-6736(75)92899-8
PMID:51193
Abstract

Glycoprotein extracts from colonic tumours were tested for blood-group precursor-like activities using human anti-I and anti-i cold agglutinins as reagents. Substantial activity was detected in the high-molecular-weight fractions of two metastatic tumours. A carcinoembryonic antigen (C.E.A.) fraction from one of these tumours was also active. The C.E.A. and the precursor-like activities were located on separate molecules. These data indicate that the levels of precursor-like antigens in entodermal tumours and their possible diagnostic value warrant detailed investigation.

摘要

相似文献

1
Blood-group precursors and cancer-related antigens.
Lancet. 1975 Aug 30;2(7931):391-3. doi: 10.1016/s0140-6736(75)92899-8.
2
Isolation, immunological characterization, and structural studies of a tumor antigen related to carcinoembryonic antigen.一种与癌胚抗原相关的肿瘤抗原的分离、免疫学特性鉴定及结构研究。
Cancer Res. 1978 Apr;38(4):1041-8.
3
Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen.从正常人体组织中鉴定出一种与癌胚抗原发生交叉反应的抗原。
Proc Natl Acad Sci U S A. 1972 Sep;69(9):2492-4. doi: 10.1073/pnas.69.9.2492.
4
Characterization of human carcinoembryonic antigens.
Johns Hopkins Med J Suppl. 1974;3:241-7.
5
Immunologically active glycopeptides derived from CEA.源自癌胚抗原的具有免疫活性的糖肽。
Ann Immunol (Paris). 1973 Nov;124(4):575-7.
6
Carcinoembryonic antigens and related glycoproteins. Molecular aspects and specificity.癌胚抗原及相关糖蛋白。分子层面与特异性。
Biochim Biophys Acta. 1983 Dec 29;695(3-4):227-49. doi: 10.1016/0304-419x(83)90013-6.
7
Demonstration of two molecular variants of carcinoembryonic antigen by concanavalin A sepharose affinity chromatography.伴刀豆球蛋白A琼脂糖亲和层析法对癌胚抗原两种分子变体的鉴定
Cancer Res. 1975 Nov;35(11 Pt 1):3001-8.
8
Preparation and isolation of immunologically active glycopeptides from carcinoembryonic antigen (CEA).从癌胚抗原(CEA)中制备和分离具有免疫活性的糖肽。
Int J Cancer. 1974 Feb 15;13(2):151-63. doi: 10.1002/ijc.2910130202.
9
Blood group N antigen precursor glycoproteins and N antigen precursor glycoproteins with Thomsen-Friedenreich (T) activity from human liver metastatic carcinomas.来自人肝转移癌的血型N抗原前体糖蛋白和具有桑森-弗里登赖希(T)活性的N抗原前体糖蛋白。
Int J Biochem. 1991;23(5-6):569-78.
10
[Immunochemical study of liver metastases of colonic tumors].[结肠肿瘤肝转移的免疫化学研究]
Pathol Biol (Paris). 1975 Feb;23(2):133-8.

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