Das G D
J Neurol Sci. 1979 Oct;43(2):193-204. doi: 10.1016/0022-510x(79)90115-1.
With the aid of [3H]thymidine autoradiography gliogenesis and ependymogenesis were studied in the brain of the rat during embryonic development. Gliogenesis was found to begin on day 17 of gestation in the caudal regions of the brain stem, and to spread rostrally. On days 20 and 21 of gestation gliogenesis reached a peak, and then declined. Ependymogenesis began earlier and showed the following pattern: day 14 of gestation in the 4th ventricle and cerebral aqueduct, day 15 in the 3rd ventricle, and day 17 in the lateral ventricles reaching a peak on different days in different sites. Both gliogenesis and ependymogensis continued up to the last day of gestation, day 22. Issues pertaining to gliogenesis and the formation of glioblasts, and the relationship between gliogenesis and ependymogenesis are discussed.
借助[3H]胸腺嘧啶核苷放射自显影技术，对大鼠胚胎发育期间脑内的神经胶质生成和室管膜生成进行了研究。发现神经胶质生成于妊娠第17天在脑干尾端区域开始，并向头端扩展。在妊娠第20天和第21天，神经胶质生成达到高峰，随后下降。室管膜生成开始得更早，呈现出以下模式：第四脑室和中脑导水管在妊娠第14天，第三脑室在妊娠第15天，侧脑室在妊娠第17天，在不同部位于不同日期达到高峰。神经胶质生成和室管膜生成均持续至妊娠最后一天，即第22天。文中讨论了与神经胶质生成、成胶质细胞形成以及神经胶质生成与室管膜生成之间关系相关的问题。
