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针对加入美国陆军的女性的风疹疫苗接种计划。

A rubella vaccination program for women entering the U.S. Army.

作者信息

Vaeth S J

出版信息

Public Health Rep. 1979 Nov-Dec;94(6):564-7.

Abstract

A voluntary rubella vaccination program for female basic trainees was initiated on April 21, 1975, at Fort Jackson, S.C. A total of 29,852 women were tested for rubella titers between April 21, 1975, and December 31, 1977, and 6,167 were found to be nonimmune. An average of 53 percent of the susceptible women were vaccinated. The best results were obtained from August 1 to December 31, 1977, when 67 percent of the susceptible women were vaccinated. During this period, blood specimens for rubella titer and for pregnancy testing were obtained simultaneously. This procedure reduced the number of referrals to the Obstetrics-Gynecology Clinic, as well as the amount of training time lost when pregnancy testing and rubella titer testing were done on separate days. Despite the vaccination program, however, rubella epidemics occurred among female trainees at Fort Jackson in 1975, 1976, and 1977. A significant number of women are still susceptible to rubella. To reduce morbidity and the risk of congenital rubella syndrome, rubella titer testing and immunization of susceptibles should be considered for women-especially where they can be screened, counseled, and vaccinated en masse.

摘要

1975年4月21日,南卡罗来纳州杰克逊堡启动了一项针对女性基础训练学员的风疹自愿接种计划。1975年4月21日至1977年12月31日期间,共有29,852名女性接受了风疹抗体检测,其中6,167人被发现无免疫力。平均有53%的易感女性接种了疫苗。1977年8月1日至12月31日期间取得了最佳效果,当时67%的易感女性接种了疫苗。在此期间,同时采集了风疹抗体检测和妊娠检测的血样。这一程序减少了转诊至妇产科诊所的人数,以及在不同日期进行妊娠检测和风疹抗体检测时所损失的训练时间。然而,尽管实施了接种计划,1975年、1976年和1977年杰克逊堡的女性学员中仍发生了风疹疫情。仍有相当数量的女性对风疹易感。为降低发病率和先天性风疹综合征的风险,应考虑对女性进行风疹抗体检测和对易感者进行免疫接种——尤其是在能够对她们进行大规模筛查、咨询和接种的地方。

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Failure of rubella herd immunity during an epidemic.风疹流行期间群体免疫失败。
N Engl J Med. 1973 Jan 11;288(2):69-72. doi: 10.1056/NEJM197301112880204.
4
Unresolved issues in the first five years of the rubella immunization program.
Am J Obstet Gynecol. 1976 Feb 15;124(4):327-32. doi: 10.1016/0002-9378(76)90088-0.
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Controlling rubella: problems and perspectives.风疹防控:问题与展望
Ann Intern Med. 1975 Sep;83(3):412-7. doi: 10.7326/0003-4819-83-3-412.
6
Epidemiologic survey of rubella in a military recruit population.新兵群体中风疹的流行病学调查。
Am J Epidemiol. 1975 May;101(5):431-7. doi: 10.1093/oxfordjournals.aje.a112110.
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Benefit-cost analysis of rubella vaccination policy.风疹疫苗接种政策的成本效益分析。
N Engl J Med. 1976 Feb 5;294(6):306-10. doi: 10.1056/NEJM197602052940604.

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