孕酮和睾酮对干扰素产生以及雌酮和氢化可的松的病毒感染增强活性的影响。
Effect of progesterone and testosterone on interferon production and on the viral infection-enhancing activity of estrone and hydrocortisone.
作者信息
Giron D J, Schmidt J P, Pindak F F
出版信息
Infect Immun. 1971 Nov;4(5):537-40. doi: 10.1128/iai.4.5.537-540.1971.
Abstract
The effect of progesterone and testosterone on interferon production and on the viral infection-enhancing (VIE) activity of estrone and hydrocortisone was investigated. Neither hormone interfered with interferon production. Progesterone reduced the VIE activity of estrone but not that of hydrocortisone. Testosterone had no effect on the VIE activity of either hormone. It is concluded that the lack of VIE activity by progesterone and testosterone may be related to their inabilities to suppress interferon production. The interference by progesterone with the VIE activity of estrone suggests that, in this system, the two hormones may affect common target cells.
摘要
研究了孕酮和睾酮对干扰素产生以及对雌酮和氢化可的松的病毒感染增强（VIE）活性的影响。两种激素均未干扰干扰素的产生。孕酮降低了雌酮的VIE活性，但未降低氢化可的松的VIE活性。睾酮对这两种激素的VIE活性均无影响。得出的结论是，孕酮和睾酮缺乏VIE活性可能与其无法抑制干扰素产生有关。孕酮对雌酮VIE活性的干扰表明，在该系统中，这两种激素可能影响共同的靶细胞。
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本文引用的文献
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