Schmidt K R, Pfeifer K J, Welter H, Welter G
Rontgenblatter. 1979 Dec;32(12):669-74.
On comparing an ionic contrast medium with a contrast medium containing one or two mg Lidocain/ml contrast medium, the one with the higher Lidocain addition was found to be most effective in respect of pain alleviation. The feeling of flush could not be favourably influenced. The use of a higher dose of Lidocain in the contrast medium may involve more pronounced circulatory reactions, such as drop in blood pressure and enhanced pulse rate. Besides, the rate of side effects compared with the use of the pure contrast medium and contrast medium with one mg Lidocain/ml CM will be increased. For this reason, it is not recommended to add more than 1 mg/ml Lidocain to the contrast medium. In most cases, repeat examinations can be effected without any risk with 1 mg Lidocain/ml contrast medium. No absolute contraindications were found in the application to outpatients and risk patients. Relative contraindication exists in patients with bradycardia and bradyarrhythmia. Following preliminary injection of a vasodilatory substance, the Lidocain/contrast medium mixture is well suited for arteriography in the arm.
将离子型造影剂与每毫升造影剂含1或2毫克利多卡因的造影剂进行比较时，发现利多卡因添加量较高的那种造影剂在减轻疼痛方面最有效。潮红的感觉无法得到有利影响。在造影剂中使用更高剂量的利多卡因可能会引发更明显的循环反应，如血压下降和脉搏加快。此外，与使用纯造影剂和每毫升造影剂含1毫克利多卡因的造影剂相比，副作用发生率会增加。因此，不建议在造影剂中添加超过1毫克/毫升的利多卡因。在大多数情况下，使用每毫升造影剂含1毫克利多卡因进行重复检查没有任何风险。在门诊患者和风险患者的应用中未发现绝对禁忌症。心动过缓和缓慢性心律失常患者存在相对禁忌症。在预先注射血管扩张物质后，利多卡因/造影剂混合物非常适合手臂动脉造影。
