Schmidt K R, Pfeifer K J
MMW Munch Med Wochenschr. 1980 Aug 22;122(34):1159-62.
The efficacy of addition of lidocaine to the conventional contrast medium has been statistically verified by the results of angiography of 342 legs and 25 arms. The investigation is painless or only slightly painful for most patients but the feeling of heat cannot be eliminated. A higher dose of lidocaine and the preliminary injection of Valium certainly improve the results of the investigation slightly, but give rise to a higher incidence of side-effects (fall in blood pressure, sleepiness). Serious complication have not been observed even in the large number of patients with risk factors.
对342条腿和25只手臂进行血管造影的结果已从统计学上证实了在传统造影剂中添加利多卡因的有效性。该检查对大多数患者来说无痛或仅有轻微疼痛，但热感无法消除。较高剂量的利多卡因和预先注射安定确实能略微改善检查结果，但会导致更高的副作用发生率（血压下降、嗜睡）。即使在大量有危险因素的患者中也未观察到严重并发症。
