Kilham H, Tooley M, Silverman M
Thorax. 1979 Oct;34(5):582-6. doi: 10.1136/thx.34.5.582.
To examine further the relation between type of exercise, workload, ventilation, and exercise-induced asthma, we compared treadmill walking with treadmill running and treadmill running with isocapnic hyperventilation in separate studies in children and adolescents. Inspired air conditions were identical during each pair of tests. Walking and running with similar minute ventilation and oxygen consumption were followed by similar falls in peak expiratory flow rate as were running and hyperventilation with similar minute ventilation and end-tidal carbon dioxide tension. This study supports the concept that hyperventilation is a central mechanism in exercise-induced asthma.
为了进一步研究运动类型、运动量、通气与运动诱发哮喘之间的关系，我们在儿童和青少年的不同研究中，将跑步机行走与跑步机跑步以及跑步机跑步与等碳酸通气进行了比较。在每对测试中，吸入空气条件相同。分钟通气量和耗氧量相似的行走和跑步后，呼气峰值流速的下降与分钟通气量和呼气末二氧化碳分压相似的跑步和通气后的下降相似。本研究支持了过度通气是运动诱发哮喘的核心机制这一概念。
