Pohle W, Rüthrich H L, Popov N, Matthies H
Acta Biol Med Ger. 1979;38(1):53-63.
Using a brigthness discrimination model in rats, the labeling of discrete hippocampus formation structures was studied after intraventricular application of [3H]-fucose. This substance was injected 5 min before training as well as 5 min, 3, 7 and 23 h after training, the pulse period lasting 120 min in all cases. A significantly training-related enhanced labeling of CA1, CA3 and CA4 cell bodies and fibres revealed that a biphasic time course occurring when radioactive fucose was applied 5 min before training and 7 h after training, whereas the increased labeling of area dentata structures was evidenced only after application of radioactive fucose 5 min before and after training. In all structures under investigation the training-related increase in labeling was more pronounced in the fibre layers than in the pyramidal and granular cell bodies.
利用大鼠的亮度辨别模型，在脑室内注射[3H]-岩藻糖后，研究离散海马结构的标记情况。该物质在训练前5分钟以及训练后5分钟、3小时、7小时和23小时注射，所有情况下脉冲期持续120分钟。CA1、CA3和CA4细胞体及纤维的标记与训练显著相关增强，表明当在训练前5分钟和训练后7小时应用放射性岩藻糖时会出现双相时间进程，而齿状回结构标记增加仅在训练前后5分钟应用放射性岩藻糖后得到证实。在所有研究的结构中，与训练相关的标记增加在纤维层比在锥体细胞和颗粒细胞体中更明显。
