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甲氧氯普胺诱导性腺功能减退男性释放生长激素。

Metoclopramide induced growth hormone release in hypogonadal males.

作者信息

Cohen H N, Hay I D, Beastall G H, Thomson J A

出版信息

Clin Endocrinol (Oxf). 1979 Jul;11(1):95-7. doi: 10.1111/j.1365-2265.1979.tb03051.x.

DOI:10.1111/j.1365-2265.1979.tb03051.x
PMID:519873
Abstract

The growth hormone (GH) response to 10 mg intravenous metoclopramide (MCP) ('Maxolon'--Beecham Laboratories) was determined in ten hypogonadal adult males. All the subjects responded with a peak growth hormone level greater than 14 mU/l within 1 hour of administration of MCP. Seven normal adult males did not respond to MCP administration. It is concluded that MCP stimulation may be a useful test for both prolactin and growth hormone reserve in hypogonadal males.

摘要

在10名性腺功能减退的成年男性中测定了生长激素(GH)对10毫克静脉注射甲氧氯普胺(MCP,“胃复安”——比彻姆实验室)的反应。所有受试者在注射MCP后1小时内生长激素水平峰值均超过14 mU/l。7名正常成年男性对注射MCP无反应。结论是,MCP刺激试验可能是评估性腺功能减退男性催乳素和生长激素储备的一项有用检测。

相似文献

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Metoclopramide induced growth hormone release in hypogonadal males.甲氧氯普胺诱导性腺功能减退男性释放生长激素。
Clin Endocrinol (Oxf). 1979 Jul;11(1):95-7. doi: 10.1111/j.1365-2265.1979.tb03051.x.
2
Metoclopramide stimulation: a test of growth hormone reserve in adolescent males.甲氧氯普胺刺激试验:青春期男性生长激素储备的一项测试。
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The prolactin response to metoclopramide in growth hormone deficient adolescent males.生长激素缺乏的青春期男性对胃复安的催乳素反应。
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The metoclopramide test: a useful tool with the luteinizing hormone-releasing hormone test in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism.胃复安试验:一种在区分体质性青春期延迟和低促性腺激素性性腺功能减退方面与促黄体生成素释放激素试验一样有用的工具。
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引用本文的文献

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Effect of metoclopramide on serum growth hormone levels in cirrhotic men.甲氧氯普胺对肝硬化男性血清生长激素水平的影响。
J Endocrinol Invest. 1983 Apr;6(2):101-5. doi: 10.1007/BF03350580.
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Cholinergic and histaminergic involvement in the growth hormone releasing effect of an enkephalin analog FK 33-824 in man.胆碱能和组胺能在脑啡肽类似物FK 33 - 824对人体生长激素释放作用中的参与情况。
Psychopharmacology (Berl). 1983;80(2):120-4. doi: 10.1007/BF00427953.
3
Clinical and pharmacological characterization of anomalous metoclopramide-induced growth hormone secretion in insulin-dependent diabetes mellitus.
胰岛素依赖型糖尿病中胃复安异常诱导生长激素分泌的临床和药理学特征
Acta Diabetol Lat. 1989 Apr-Jun;26(2):133-45. doi: 10.1007/BF02581365.
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Some current aspects of clinical and experimental neuroendocrinology with particular reference to growth hormone, thyrotropin and prolactin.临床与实验神经内分泌学的一些当前研究方面,特别涉及生长激素、促甲状腺激素和催乳素。
J Endocrinol Invest. 1979 Jul-Sep;2(3):307-31. doi: 10.1007/BF03350424.