Gunz F W, Spears G F
Br Med J. 1968 Dec 7;4(5631):604-8. doi: 10.1136/bmj.4.5631.604.
The distribution of leukaemia in time and space was examined by tracing the date of onset and the place of residence in all cases of childhood leukaemia and of acute leukaemia in adults, totalling 1,003 cases, which occurred in New Zealand during the 12 years from 1953 to 1964.Significant seasonal variations in the onset were found in adults but not in children. Time-space clustering did not occur in adults, but a significant tendency towards it was found in children aged less than 6 years. Since a similar tendency has previously been found by two other groups of investigators it is suggested that leukaemia in young children may have a different aetiology from that occurring at other ages.
通过追溯1953年至1964年这12年间在新西兰发生的所有儿童白血病病例和成人急性白血病病例（共计1003例）的发病日期和居住地，研究了白血病在时间和空间上的分布情况。结果发现成人发病有显著的季节性变化，而儿童则没有。成人未出现时空聚集现象，但在6岁以下儿童中发现了显著的聚集倾向。由于另外两组研究人员此前也发现了类似的倾向，因此有人提出幼儿白血病的病因可能与其他年龄段的白血病不同。
