小鼠对同基因或自体睾丸细胞的免疫反应。I. 环磷酰胺处理小鼠中增强的迟发型足垫反应。
Immune response to syngeneic or autologous testicular cells in mice. I. Augmented delayed footpad reaction in cyclophosphamide-treated mice.
作者信息
Yoshida S, Nomoto K, Himeno K, Takeya K
出版信息
Clin Exp Immunol. 1979 Nov;38(2):211-7.
Abstract
A delayed footpad reaction against syngeneic or autologous testicular cells was detected in mice of inbred C57BL/6, AKR and C3H/He strains. The reaction was only provoked to a measurable level if the immunization was preceded by treatment with cyclophosphamide (CY). Footpad reaction was strongest on day 6 after immunization and was detected in both male and female mice. It was found that the reaction was elicited not only with the immunizing antigen, but also with allogeneic or xenogeneic testicular antigen in mice immunized with syngeneic testicular cells.
摘要
在近交系C57BL/6、AKR和C3H/He品系的小鼠中检测到对同基因或自体睾丸细胞的迟发型足垫反应。只有在免疫前用环磷酰胺（CY）处理，反应才会激发到可测量的水平。足垫反应在免疫后第6天最强，在雄性和雌性小鼠中均能检测到。研究发现，在用同基因睾丸细胞免疫的小鼠中，不仅免疫抗原能引发反应，同种异体或异种睾丸抗原也能引发反应。
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