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豚鼠对同基因或异种基因睾丸细胞的迟发型超敏反应。

Delayed hypersensitivity to syngeneic or xenogeneic testicular cells in guinea-pigs.

作者信息

Yoshida S, Nomoto K, Himeno K, Sanui H

出版信息

Immunology. 1981 Mar;42(3):445-9.

Abstract

Guinea-pigs of an inbred JY-l strain were immunized with syngeneic or xenogeneic testicular cells without added adjuvants. A delayed erythematous skin reaction accompanied by basophil infiltration was detected after elicitation with syngeneic testicular cells and the erythematous reaction was augmented by treatment with cyclophosphamide before immunization. Cross-reactivity was observed among testicular cells of the guinea-pig, rat or mouse at the levels of immunization and elicitation.

摘要

用同基因或异基因睾丸细胞对近交JY-l品系豚鼠进行免疫,不添加佐剂。用同基因睾丸细胞激发后,检测到伴有嗜碱性粒细胞浸润的迟发性红斑皮肤反应,且在免疫前用环磷酰胺治疗可增强红斑反应。在免疫和激发水平上,观察到豚鼠、大鼠或小鼠的睾丸细胞之间存在交叉反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6e7/1458443/f26efececb73/immunology00244-0081-a.jpg

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