Rees W D, Go V L, Malagelada J R
Gut. 1979 Nov;20(11):963-70. doi: 10.1136/gut.20.11.963.
In six healthy individuals, the relationship between antroduodenal motor activity, duodenogastric reflux, and gastric emptying were simultaneously examined by combined use of multiple marker perfusion and miniature strain gauge transducers. An interdigestive pattern of motor activity was observed during the fasting period;duodenogastric reflux was of variable magnitude, but reproducible in each individual. Fasting reflux was significantly reduced during phase III of the interdigestive complex. Administration of 0.15 M sodium chloride into the stomach resulted in minor and inconsistent changes in antroduodenal motility, despite the rapid and similar pattern of gastric emptying in the six subjects. This study supports the concept that motor activity in the antroduodenal region does not affect gastric emptying of inert, isotonic fluids but may be involved in the regulation of duodenogastric reflux.
在6名健康个体中，通过联合使用多种标记物灌注法和微型应变片传感器，同时检测了胃十二指肠运动活性、十二指肠-胃反流和胃排空之间的关系。在禁食期观察到一种消化间期的运动模式；十二指肠-胃反流程度各异，但在每个个体中均可重复出现。在消化间期复合波的Ⅲ期，禁食时的反流显著减少。尽管6名受试者的胃排空速度快且模式相似，但向胃内注入0.15M氯化钠后，胃十二指肠运动仅出现轻微且不一致的变化。本研究支持以下观点，即胃十二指肠区域的运动活性不影响惰性等渗液体的胃排空，但可能参与十二指肠-胃反流的调节。
